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Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
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Multi-Omics Applications in Adult Acute Lymphoblastic Leukemia: From Biological Mechanisms to Precision Therapies. [PDF]
Simio C, Molica M, De Fazio L, Rossi M.
europepmc +1 more source
Evolution of the HIV-1 integration site landscape and inducible reservoir in early-treated people. [PDF]
Struyve T +8 more
europepmc +1 more source
Clonal tracing of rare anal metastasis in esophageal squamous cell carcinoma: a case report with whole-exome sequencing and multimodal therapy. [PDF]
Jiang Y +5 more
europepmc +1 more source
Computational strategies in tumor phylogenetics: evaluating multimodal integration and methodological trade-offs across study designs. [PDF]
Jiang C, Wang Z, Wang R, Liang S, Tao S.
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Clonal integration increases tolerance of a phalanx clonal plant to defoliation
Science of The Total Environment, 2017Defoliation by herbivores commonly imposes negative effects on plants, and physiological integration (resource sharing) can enhance the ability of guerilla clonal plants to tolerate stresses. Here we examined whether physiological integration can increase the ability of phalanx clonal plants to withstand defoliation.
Pu Wang +7 more
openaire +4 more sources
Clonal integration enhances performance of an invasive grass
Oikos, 2020While many clonal plants are highly successful invaders, the contribution of clonal integration (i.e. the translocation of resources among ramets) to invasion is often unknown. We used model simulations to ask if clonal integration would facilitate photosynthate translocation, if the performance of daughter ramets might be enhanced
James A. Estrada +2 more
openaire +1 more source

