Results 101 to 110 of about 102,227 (239)

Status of the "YSG Biotech" program of building up teak genetic resources in Sabah [PDF]

, 2009
Depuis le début des années 1990, le Plant Biotechnology Laboratory, projet de collaboration en recherche et développement entre la Division Forestière du Yayasan Sabah Group et le Centre de coopération internationale en recherche agronomique pour le ...
Goh, Doreen Kim Soh, Monteuuis, Olivier
core  

Considering Intra-individual Genetic Heterogeneity to Understand Biodiversity [PDF]

, 2019
In this chapter, I am concerned with the concept of Intra-individual Genetic Hetereogeneity (IGH) and its potential influence on biodiversity estimates. Definitions of biological individuality are often indirectly dependent on genetic sampling -and vice ...
A Cárdenas-Flores, A Roger, A Roger, AV Gonzalez, B Rinkevich, B Rinkevich, B Santelices, B Santelices, B Santelices, B Santelices, B Santelices, B Santelices, B Santelices, B Santelices, B Santelices, B Wang, C Angelard, C Wagg, DC Queller, DC Queller, DE Gill, DJ Herman, DS Wilson, E Boon, E Boon, E Boon, E Boon, E Clarke, G Kuhn, H Youssoufian, HJ Folse, HJ Folse, I Matos, I Zarraonaindia, IR Sanders, J Marleau, J Maynard Smith, J Vijg, JE Strassmann, JE Strassmann, JJ Morris, JO McInerney, JT Bonner, JT Staley, K Monro, L Collado-Vides, LW Buss, M Giovannetti, M Hijri, M O’Malley, M Pineda-Krch, M Pineda-Krch, M Schweinsberg, ME Samuels, MG Heijden van der, N Corradi, NB Spinner, P Bonfante, R Riley, RE Michod, RP Erickson, S Okasha, S Sarkar, S. Andrew Inkpen, T Fagerström, T Pradeu, T Wernberg, T Wyss, WF Doolittle, WF Doolittle   +69 more
core   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Context-Dependent Parental Effects on Clonal Offspring Performance

Frontiers in Plant Science, 2018
Parental environments may potentially affect offspring fitness, and the expression of such parental effects may depend on offspring environments and on whether one considers an individual offspring or all offspring of a parent.
Bi-Cheng Dong, Mark van Kleunen, Mark van Kleunen, Fei-Hai Yu, Fei-Hai Yu, Fei-Hai Yu   +5 more
doaj   +1 more source

Effective population size in a partially clonal plant is not predicted by the number of genetic individuals. [PDF]

Evol Appl, 2023
Gargiulo R, Waples RS, Grow AK, Shefferson RP, Viruel J, Fay MF, Kull T.   +6 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Is Clonal Integration a Buffer for the Stress of Resource Acquisition Depletion in Eichhornia crassipes (Pontederiaceae) Ramets?

Stresses
Natural selection favors the allocation of finite resources to different functions maximizing fitness. In this sense, some functions may decrease whereas others increase when resources are limited in a process called a trade-off. However, a great variety
Guilherme Ramos Demetrio, Dalton Serafim, Flávia de Freitas Coelho   +2 more
doaj   +1 more source

Predictable and stable epimutations induced during clonal plant propagation with embryonic transcription factor. [PDF]

PLoS Genet, 2022
Wibowo AT, Antunez-Sanchez J, Dawson A, Price J, Meehan C, Wrightsman T, Collenberg M, Bezrukov I, Becker C, Benhamed M, Weigel D, Gutierrez-Marcos J.   +11 more
europepmc   +1 more source

Achievements and problems in the implementation of microcutting technology for clonaI rubber rootstock propagation

, 2008
Microcutting is one of in vitro plant propagation methods and has been developed for rubber (Hevea brasiliensis) by using axillary buds from young seedlings as explant sources.
Carron, Marc-Philippe, Nurhaimi-Haris,, Siswanto,, Sumarmadji,, Sumaryono,   +4 more
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