Results 211 to 220 of about 80,571 (261)
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Clonal and non-clonal chromosome aberrations and genome variation and aberration
Genome, 2006The theoretical view that genome aberrations rather than gene mutations cause a majority of cancers has gained increasing support from recent experimental data. Genetic aberration at the chromosome level is a key aspect of genome aberration and the systematic definition of chromosomal aberrations with their impact on genome variation and cancer genome ...
Henry H Q, Heng +5 more
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Genomic variation in Trypanosoma cruzi clonal cultures
Parasitology Research, 1996Spontaneous changes in restriction DNA profiles and pulsed-field gel electrophoresis (PFGE) patterns, along with a concomitant loss of infectivity, were observed in infective clones of Trypanosoma cruzi strain Y either following a number of passages during the exponential growth phase of after subcloning in liver infusion tryptone (LIT) medium using as
A M, Alves +2 more
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Mitigating Clonal Variation in Recombinant Mammalian Cell Lines
Trends in Biotechnology, 2019Mammalian expression platforms are primary production systems for therapeutic proteins that require complex post-translational modifications. Current processes used for developing recombinant mammalian cell lines generate clonal cell lines with high phenotypic heterogeneity, which has puzzled researchers that use mammalian cell culture systems for a ...
Jae Seong, Lee +3 more
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Clonal crops show structural variation role in domestication
Nature Plants, 2019The efficient use of clonal reproduction through vegetative propagation is one of the underlying reasons for the great success of the angiosperms, enabling stabilized and adapted phenotypes to rapidly expand into suitable environments1. This stability of phenotype has made clonal systems attractive for domestication, accounting for about half of all ...
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Human Pathology, 1998
The majority of posttransplant lymphoproliferative disorders (PTLD) are Epstein-Barr virus (EBV)-associated and of B-cell origin. A much smaller proportion of PTLD are of T-cell origin. We report the clinical, morphological, immunophenotypic, and genotypic results of a unique PTLD, initially diagnosed as immune mediated thrombocytopenia (ITP), which at
B P, Nelson +4 more
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The majority of posttransplant lymphoproliferative disorders (PTLD) are Epstein-Barr virus (EBV)-associated and of B-cell origin. A much smaller proportion of PTLD are of T-cell origin. We report the clinical, morphological, immunophenotypic, and genotypic results of a unique PTLD, initially diagnosed as immune mediated thrombocytopenia (ITP), which at
B P, Nelson +4 more
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Science of The Total Environment, 2019
Clonal plant species can produce genetically identical and potentially independent offspring, and dominate a variety of habitats. The divergent evolutionary mechanisms between clonal and non-clonal plants are interesting areas of ecological research.
Ji-Zhong, Wan +2 more
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Clonal plant species can produce genetically identical and potentially independent offspring, and dominate a variety of habitats. The divergent evolutionary mechanisms between clonal and non-clonal plants are interesting areas of ecological research.
Ji-Zhong, Wan +2 more
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Phenotypic variation in clonal Abelson virus lymphoma cells.
The Journal of Immunology, 1985Abstract Two clonal A-MuLV lymphoma cell lines have the capacity to generate phenotypic variants when grown in vivo as ascites tumors. Variant lines differed from parental lymphoma cells in their expression of enzymatic or cell surface differentiation markers.
P L, Green +8 more
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Clonal Variation in Cereals and Forage Grasses
1998Clonal changes in tissue culture have proved to be a useful method for creating desirable variants in most cereal crops. Variants include changes in physiological mechanisms, agronomic characteristics, plant type, and resistance to pests and stress conditions.
M. C. Rush +5 more
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Variation and Clonal Structure in a Unisexual Fish
The American Naturalist, 1978A genetic analysis of population structure in the unisexual fish, Poeciliopsis monacha-lucida, was conducted using protein phenotypes encoded by 22 loci. The all-female populations arose by hybridization between P. monacha and P. lucida in narrow zones where their ranges overlap. The unisexual hybrids are sustained by mating with males of P. lucida and
Robert C. Vrijenhoek +2 more
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