Results 1 to 10 of about 514,530 (316)

Characterization and comparison of 2 distinct epidemic community-associated methicillin-resistant Staphylococcus aureus clones of ST59 lineage. [PDF]

PLoS ONE, 2013
Sequence type (ST) 59 is an epidemic lineage of community-associated (CA) methicillin-resistant Staphylococcus aureus (MRSA) isolates. Taiwanese CA-MRSA isolates belong to ST59 and can be grouped into 2 distinct clones, a virulent Taiwan clone and a ...
Chih-Jung Chen, Clemens Unger, Wolfgang Hoffmann, Jodi A Lindsay, Yhu-Chering Huang, Friedrich Götz   +5 more
doaj   +1 more source

Hydrogen Peroxide Promotes the Production of Radiation-Derived EVs Containing Mitochondrial Proteins

Antioxidants, 2022
In spite of extensive successes, cancer recurrence after radiation treatment (RT) remains one of the significant challenges in the cure of localized prostate cancer (PCa).
Caitlin E. Miller, Fangfang Xu, Yanming Zhao, Wei Luo, Weixiong Zhong, Kristy Meyer, Rani Jayswal, Heidi L. Weiss, William H. St. Clair, Daret K. St. Clair, Luksana Chaiswing   +10 more
doaj   +1 more source

Generation of hypoimmunogenic universal iPS cells through HLA-type gene knockout

Experimental and Molecular Medicine
Hypoimmunogenic universal induced pluripotent stemn (iPS) cells were generated through the targeted disruption of key genes, including human leukocyte antigen (HLA)-A, HLA-B and HLA-DR alpha (DRA), using the CRISPR–Cas9 system.
Juryun Kim, Yoojun Nam, Doyeong Jeon, Yujin Choi, SeonJu Choi, Chang Pyo Hong, Siyoung Kim, Hyerin Jung, Narae Park, Yeowon Sohn, Yeri Alice Rim, Ji Hyeon Ju   +11 more
doaj   +1 more source

miR-513b-5p inhibits the proliferation and promotes apoptosis of retinoblastoma cells by targeting TRIB1

Open Medicine, 2021
MicroRNAs are involved in the pathogenesis of various human malignant tumors. This study aims to explore the role of miR-513b-5p in the malignant proliferation of retinoblastoma (RB) cells and its potential molecular mechanisms.
Zhang Li-Juan, Wang Fang, Qi Pei-Yan, Zhou Wei-Yan, Wang Bing   +4 more
doaj   +1 more source

Cloning of Canine Osteosarcoma Cells.

Journal of Veterinary Medical Science, 1995
Six clonal cells were established from a canine osteosarcoma cell line (POS) by a limiting dilution method using feeder cells. Whereas histology of mass developed in nude mice by transplantation of POS cells revealed various cell types, clonal cells were morphologically consistent in size and shape.
NOZAKI, Kazutoshi, OKUYAMA, Kayoko, KADOSAWA, Tsuyoshi, NAKAYAMA, Hiroyuki, GOTO, Naoaki, SASAKI, Nobuo, TAKEUCHI, Akira   +6 more
openaire   +3 more sources

Phenotypical and functional characterization of a HepG2 cell clone stably overexpressing cytochrome P450 (CYP) 2C9

BMC Research Notes
Objective We aimed to generate a HepG2 cell clone stably overexpressing cytochrome P450 (CYP) 2C9 together with an empty vector (EV) control cell clone for pharmacological and toxicological studies of substances with CYP2C9-mediated biotransformation ...
Sarah Kammerer, Natalie Herzog, Thea Jenchen, Valentina Stock, Rebecca Hofer, Veronika Ruzsanyi, Jan-Heiner Küpper   +6 more
doaj   +1 more source

Characterization of HTLV-1 Infectious Molecular Clone Isolated from Patient with HAM/TSP and Immortalization of Human Primary T-Cell Lines

Viruses
Human T-cell leukemia virus (HTLV-1) is the etiological agent of lymphoproliferative diseases such as adult T-cell leukemia and T-cell lymphoma (ATL) and a neurodegenerative disease known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM ...
Marcia Bellon, Pooja Jain, Christophe Nicot   +2 more
doaj   +1 more source

Alterations in integrin expression modulates invasion of pancreatic cancer cells

Journal of Experimental & Clinical Cancer Research, 2009
Background Factors mediating the invasion of pancreatic cancer cells through the extracellular matrix (ECM) are not fully understood. Methods In this study, sub-populations of the human pancreatic cancer cell line, MiaPaCa-2 were established which ...
Crown John, Clynes Martin, Walsh Naomi, O'Donovan Norma   +3 more
doaj   +1 more source

Prognostic Biomarker NUMB Is Inhibited by Breast Cancer Cell Exosomes to Promote Breast Cancer Progression

Journal of Immunology Research, 2022
Objective. To clarify the regulation of breast cancer cell-derived exosomes on breast cancer and the expression of the NUMB endocytic adaptor protein (NUMB) protein. Methods. The exosomes of breast cancer cell line MDA-MB-231 were isolated.
Xue Qin, Youde Cao
doaj   +1 more source

Cloning human stem cells [PDF]

Canadian Medical Association Journal, 2004
![Figure][1] Figure. Photo by: Myra Rudakewich Pluripotent human embryonic stem cells have a unique ability to differentiate into any cell line. Although this has raised hopes that transplantation of stem cells may halt or reverse degenerative disorders such as diabetes and Parkinson ...
openaire   +2 more sources