Long-term cultivation of two diploid epithelial cell lines derived from normal rat liver cells [PDF]
To obtain a useful rat liver cell line for in vitro carcinogenesis, two rat diploid epithelial cell lines were established from a 7-day-old male rat by the repeated colonial clone method.
Nakabayashi, Hidekazu +2 more
core +1 more source
Homing of the Myeloma Cell Clone [PDF]
The presence of myeloma cells in the blood circulation. implicates that these cells must have the potential to extravasate and home to the bone marrow environment. Using the 5T2 MM mouse model, we could demonstrate that the restricted localization of myeloma cells in the bone marrow is the result of selective migration of myeloma cells in the bone ...
Vanderkerken, Karin +5 more
openaire +3 more sources
We previously identified a TCR Vβ21 T cell clone which was specific to CML patients, and demonstrated that TCR Vα13/β21 gene-modified CD3+ T cells had specific cytotoxicity for HLA-A11+ K562 cells.
Yikai Zhang +5 more
doaj +1 more source
Stem cells of Hydra magnipapillata can differentiate into somatic cells and germ line cells [PDF]
We investigated whether all stem cells of Hydra can differentiate both somatic cells and gametes or if a separate germ line exists in these phylogenetically old organisms.
Bosch, Thomas C. G., David, Charles N.
core +1 more source
Immune-mediated competition in rodent malaria is most likely caused by induced changes in innate immune clearance of merozoites [PDF]
Malarial infections are often genetically diverse, leading to competitive interactions between parasites. A quantitative understanding of the competition between strains is essential to understand a wide range of issues, including the evolution of ...
Savill Nicholas Jon +19 more
core +1 more source
Modeling large fluctuations of thousands of clones during hematopoiesis: The role of stem cell self-renewal and bursty progenitor dynamics in rhesus macaque. [PDF]
In a recent clone-tracking experiment, millions of uniquely tagged hematopoietic stem cells (HSCs) and progenitor cells were autologously transplanted into rhesus macaques and peripheral blood containing thousands of tags were sampled and sequenced over ...
Song Xu +3 more
doaj +1 more source
Background CD30, a 120 kDa surface phosphorylated protein is a member of tumour necrosis/nerve growth factor receptor (TNF/NGFR) family and constitutively expressed by Hodgkin and Reed-Sternberg (HRS) cells of Hodgkin lymphoma (HL) and the neoplastic ...
Gascoyne Randy D +5 more
doaj +1 more source
Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs [PDF]
Hepatitis E virus (HEV) is an important but extremely understudied human pathogen. Genotypes 1 and 2 are restricted to humans, whereas genotypes 3 and 4 are zoonotic, infecting both humans and pigs.
Meng, Xiang-Jin +6 more
core +1 more source
Functional activity of clone-1, clone-5 and clone-6 expressed in CaCo2 cells. [PDF]
The CaCo-2 cells were transfected with either a vector (pGL4.23), clone-1, clone-5, or clone-6. After the transfection, the luciferase activity was measured in the presence and absence of aldosterone (10 nM) treatment.
Vazhaikkurichi M. Rajendran (412638) +2 more
core +1 more source
The methyl methanesulfonate and ultraviolet-sensitive gene clone 81 protein is a structure-specific nuclease that plays important roles in DNA replication and repair.
Juan Lv +4 more
doaj +1 more source

