Results 11 to 20 of about 750,149 (308)

Characterization and comparison of 2 distinct epidemic community-associated methicillin-resistant Staphylococcus aureus clones of ST59 lineage. [PDF]

PLoS ONE, 2013
Sequence type (ST) 59 is an epidemic lineage of community-associated (CA) methicillin-resistant Staphylococcus aureus (MRSA) isolates. Taiwanese CA-MRSA isolates belong to ST59 and can be grouped into 2 distinct clones, a virulent Taiwan clone and a ...
Chih-Jung Chen, Clemens Unger, Wolfgang Hoffmann, Jodi A Lindsay, Yhu-Chering Huang, Friedrich Götz   +5 more
doaj   +9 more sources

Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480. [PDF]

PLoS ONE, 2016
Human cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) can be isolated as side population (SP) cells, aldehyde dehydrogenase high (ALDHhigh) cells or cell surface marker-positive cells including CD44+ cells and CD133+ cells. CSCs/CICs and non-
Akari Takaya, Yoshihiko Hirohashi, Aiko Murai, Rena Morita, Hiroshi Saijo, Eri Yamamoto, Terufumi Kubo, Munehide Nakatsugawa, Takayuki Kanaseki, Tomohide Tsukahara, Yasuaki Tamura, Ichiro Takemasa, Toru Kondo, Noriyuki Sato, Toshihiko Torigoe   +14 more
doaj   +1 more source

Ubiquinone analogs: a mitochondrial permeability transition pore-dependent pathway to selective cell death. [PDF]

PLoS ONE, 2010
Prolonged opening of the mitochondrial permeability transition pore (PTP) leads to cell death. Various ubiquinone analogs have been shown to regulate PTP opening but the outcome of PTP regulation by ubiquinone analogs on cell fate has not been studied ...
Flavien Devun, Ludivine Walter, Julie Belliere, Cécile Cottet-Rousselle, Xavier Leverve, Eric Fontaine   +5 more
doaj   +1 more source

How Naive T-Cell Clone Counts Are Shaped By Heterogeneous Thymic Output and Homeostatic Proliferation

Frontiers in Immunology, 2022
The specificity of T cells is that each T cell has only one T cell receptor (TCR). A T cell clone represents a collection of T cells with the same TCR sequence. Thus, the number of different T cell clones in an organism reflects the number of different T
Renaud Dessalles, Yunbei Pan, Mingtao Xia, Davide Maestrini, Maria R. D’Orsogna, Maria R. D’Orsogna, Tom Chou, Tom Chou   +7 more
doaj   +1 more source

PD-L1 expression with QR1 and E1L3N antibodies according to histological ovarian cancer subtype: A series of 232 cases

European Journal of Histochemistry, 2021
Therapeutic strategies for epithelial ovarian cancers are evolving with the advent of immunotherapy, such as PD-L1 inhibitors, with encouraging results. However, little data are available on PDL-1 expression in ovarian cancers.
Caroline Eymerit-Morin, Anna Ilenko, Thomas Gaillard, Justine Varinot, Eva Compérat, Sofiane Bendifallah, Emile Darai   +6 more
doaj   +1 more source

Antigen presentation by B cells enables epitope spreading across an MHC barrier

Nature Communications, 2023
Circumstantial evidence suggests that B cells may instruct T cells to break tolerance. Here, to test this hypothesis, we used a murine model in which a single B cell clone precipitates an autoreactive response resembling systemic lupus erythematosus (SLE)
Cecilia Fahlquist-Hagert, Thomas R. Wittenborn, Ewa Terczyńska-Dyla, Kristian Savstrup Kastberg, Emily Yang, Alysa Nicole Rallistan, Quinton Raymond Markett, Gudrun Winther, Sofie Fonager, Lasse F. Voss, Mathias K. Pedersen, Nina van Campen, Alexey Ferapontov, Lisbeth Jensen, Jinrong Huang, John D. Nieland, Cees E. van der Poel, Johan Palmfeldt, Michael C. Carroll, Paul J. Utz, Yonglun Luo, Lin Lin, Søren E. Degn   +22 more
doaj   +1 more source

Discovering and Differentiating New and Emerging Clonal Populations of Chlamydia trachomatis with a Novel Shotgun Cell Culture Harvest Assay

Emerging Infectious Diseases, 2008
Chlamydia trachomatis is the leading cause of preventable blindness and bacterial sexually transmitted diseases worldwide. Plaque assays have been used to clonally segregate laboratory-adapted C.
Naraporn Somboonna, Sally Mead, Jessica Liu, Deborah Dean   +3 more
doaj   +1 more source

Chimeric antigen receptor (CAR)-specific monoclonal antibody to detect CD19-specific T cells in clinical trials. [PDF]

PLoS ONE, 2013
Clinical trials targeting CD19 on B-cell malignancies are underway with encouraging anti-tumor responses. Most infuse T cells genetically modified to express a chimeric antigen receptor (CAR) with specificity derived from the scFv region of a CD19 ...
Bipulendu Jena, Sourindra Maiti, Helen Huls, Harjeet Singh, Dean A Lee, Richard E Champlin, Laurence J N Cooper   +6 more
doaj   +1 more source

Stem cells of Hydra magnipapillata can differentiate into somatic cells and germ line cells [PDF]

, 1987
We investigated whether all stem cells of Hydra can differentiate both somatic cells and gametes or if a separate germ line exists in these phylogenetically old organisms.
Bode, Bosch, Bosch, Bosch, Burnett, Buss, Buss, Buss, David, David, David, Diehl, Gierer, Heimfeld, Heimfeld, Lenhoff, Littlefield, Littlefield, Marcum, Marcum, Nieuwkoop, Park, Sachs, Sproull, Sugiyama, Sugiyama, Takano, Weismann, Weismann   +28 more
core   +1 more source

Homing of the Myeloma Cell Clone [PDF]

Acta Oncologica, 2000
The presence of myeloma cells in the blood circulation. implicates that these cells must have the potential to extravasate and home to the bone marrow environment. Using the 5T2 MM mouse model, we could demonstrate that the restricted localization of myeloma cells in the bone marrow is the result of selective migration of myeloma cells in the bone ...
Vanderkerken, Karin, Van Camp, Benjamin, De Greef, Catherine, Vande Broek, Isabelle, Asosingh, Kewal, Van Riet, Ivan   +5 more
openaire   +3 more sources