Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480. [PDF]
Human cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) can be isolated as side population (SP) cells, aldehyde dehydrogenase high (ALDHhigh) cells or cell surface marker-positive cells including CD44+ cells and CD133+ cells. CSCs/CICs and non-
Akari Takaya +14 more
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Hybrid clone cells derived from human breast epithelial cells and human breast cancer cells exhibit properties of cancer stem/initiating cells [PDF]
Background The biological phenomenon of cell fusion has been associated with cancer progression since it was determined that normal cell × tumor cell fusion-derived hybrid cells could exhibit novel properties, such as enhanced metastatogenic capacity or ...
Daria Gauck +4 more
doaj +2 more sources
Oxidative Stress and Apoptosis Contributed to Nonylphenol-Induced Cell Damage in Mouse NCTC Clone 1469 Cells [PDF]
Nonylphenol (NP) is considered an environmental toxicant and endocrine-disrupting compound. The present study aimed to investigate the effects of NP on NCTC Clone 1469, nonparenchymal hepatocytes, and to study the molecular basis of NP-induced liver ...
Xiaozhen Liu +7 more
doaj +2 more sources
Ubiquinone analogs: a mitochondrial permeability transition pore-dependent pathway to selective cell death. [PDF]
Prolonged opening of the mitochondrial permeability transition pore (PTP) leads to cell death. Various ubiquinone analogs have been shown to regulate PTP opening but the outcome of PTP regulation by ubiquinone analogs on cell fate has not been studied ...
Flavien Devun +5 more
doaj +1 more source
The specificity of T cells is that each T cell has only one T cell receptor (TCR). A T cell clone represents a collection of T cells with the same TCR sequence. Thus, the number of different T cell clones in an organism reflects the number of different T
Renaud Dessalles +7 more
doaj +1 more source
Stability of clone B7 reporter cells. [PDF]
(A) Comparison of luminescent biosensor activation in low passage vs. high passage reporter cells. The first freeze of clone B7 reporter cells (Passage 2) and cells kept in culture for two months (Passage 20) were infected with SARS-CoV-2 at MOI = 0.01 ...
Thomas WM Crozier (12072892) +15 more
core +1 more source
Therapeutic strategies for epithelial ovarian cancers are evolving with the advent of immunotherapy, such as PD-L1 inhibitors, with encouraging results. However, little data are available on PDL-1 expression in ovarian cancers.
Caroline Eymerit-Morin +6 more
doaj +1 more source
Chlamydia trachomatis is the leading cause of preventable blindness and bacterial sexually transmitted diseases worldwide. Plaque assays have been used to clonally segregate laboratory-adapted C.
Naraporn Somboonna +3 more
doaj +1 more source
Chimeric antigen receptor (CAR)-specific monoclonal antibody to detect CD19-specific T cells in clinical trials. [PDF]
Clinical trials targeting CD19 on B-cell malignancies are underway with encouraging anti-tumor responses. Most infuse T cells genetically modified to express a chimeric antigen receptor (CAR) with specificity derived from the scFv region of a CD19 ...
Bipulendu Jena +6 more
doaj +1 more source
Antigen presentation by B cells enables epitope spreading across an MHC barrier
Circumstantial evidence suggests that B cells may instruct T cells to break tolerance. Here, to test this hypothesis, we used a murine model in which a single B cell clone precipitates an autoreactive response resembling systemic lupus erythematosus (SLE)
Cecilia Fahlquist-Hagert +22 more
doaj +1 more source

