Journal of Neuroinflammation, 2012 Background Extracellular matrix metalloproteinase inducer (EMMPRIN; CD147, basigin) is an inducer of the expression of several matrix metalloproteinases (MMPs).
Agrawal Smriti M +4 more
doaj +1 more source
Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells. [PDF]
PLoS ONE, 2014 Timely characterization of a cancer's evolution is required to predict treatment efficacy and to detect resistance early. High content analysis of single Circulating Tumor Cells (CTCs) enables sequential characterization of genotypic, morphometric and ...
Angel E Dago +11 more
doaj +1 more source
Genetic Switch to Hypervirulence Reduces Colonization Phenotypes of the Globally Disseminated Group A Streptococcus M1T1 Clone [PDF]
, 2020 Background. The recent resurgence of invasive group A streptococcal disease has been paralleled by the emergence of the M1T1 clone. Recently, invasive disease initiation has been linked to mutations in the covR/S 2-component regulator.
Streptococcus, Jid, • Clone, A Group
core
Diagnostic Pathology, 2018 Background Immunohistochemistry (IHC) for programmed cell death ligand 1 (PD-L1) displays staining diversity. We compared IHC staining of PD-L1 in gastric cancer (GC) by using three commercially available antibody clones, and analyzed the correlation ...
Jing Ma +8 more
doaj +1 more source
Sub-localization of mineralocorticoid response elements (MRE) in clone-5 and clone-6. [PDF]
, 2014 The clone-5 was sub-cloned into thirds, clone-5A, clone-5B and clone-5C representing the left, middle and right thirds of clone-5, respectively. Clone-5A, -5B and -5C were tested for MRE/aldosterone responsiveness in the HEK293T cells.
Vazhaikkurichi M. Rajendran (412638) +2 more
core +1 more source
In vivo differentiation of mast cells from acute myeloid leukemia blasts carrying a novel activating ligand-independent C-kit mutation [PDF]
, 1998 The primary role of protooncogene c-kit in mast cell differentiation is supported by the development of mast cells from CD34+/CD117+(c-kit) myeloid precursors.
L. Larizza +3 more
core +1 more source
Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse. [PDF]
PLoS ONE, 2015 Induced pluripotent stem cells (iPSCs) have tremendous potential as a tool for disease modeling, drug testing, and other applications. Since the generation of iPSCs "captures" the genetic history of the individual cell that was reprogrammed, iPSC clones (
Cheng Li +11 more
doaj +1 more source
Resident phenotypically modulated vascular smooth muscle cells in healthy human arteries. [PDF]
, 2012 Vascular interstitial cells (VICs) are non-contractile cells with filopodia previously described in healthy blood vessels of rodents and their function remains unknown.
Reddy, M +10 more
core +1 more source
Haematologica, 2010 Background Clones of glycosylphosphatidylinositol-anchor protein-deficient cells are characteristic in paroxysmal nocturnal hemoglobinuria and are present in about 40–50% of patients with severe aplastic anemia.
Phillip Scheinberg +3 more
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Di-san junyi daxue xuebao, 2020 Objective To study the effect of down-regulation of long non-coding RNA (lncRNA) HOXA cluster antisense RNA 2 (HOXA-AS2)/miR-20a pathway on apoptosis and invasion of skin squamous cell carcinoma cells in vitro.
XU Wen, LIU Xuhong, LIU Hua
doaj +1 more source