Results 121 to 130 of about 29,987 (218)

Monoclonal Annular Lichenoid Dermatitis of Youth as a New Entity: A Case Report and Review of the Literature. [PDF]

Int J Mol Sci
Tockova O, Hosta V, Rucigaj TP, Ponorac S, Kokovic I, Calonje E, Luzar B.   +6 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Exploring clonality of <i>Mannheimia haemolytica</i> in beef cattle. [PDF]

Microbiol Spectr
Hacker ND, Scott MA, Pinnell LJ, Doster E, Crosby WB, Woolums AR, Klima CL, Morley PS, Valeris-Chacin R.   +8 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Dynamics of Spinal Fluid Immune Cell Alterations Following Cladribine Tablet Treatment in Multiple Sclerosis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Smirnov RA, Cantoni C, Lee K, Agnihotri RA, Axtell RC, Salter A, Lancia S, Paley MA, Hayward B, Korich J, Evans E, Pardo G, Obeidat AZ, Stuve O, Bar-Or A, Artyomov MN, Cross AH, Edelson BT, Wu GF.   +18 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Confined B-Cell Reconstruction and High T-Cell Clonality Define Clinical Response to Cladribine Treatment. [PDF]

Ann Neurol
Schneider-Hohendorf T, Eveslage M, Wirth T, Wünsch C, Schumann EM, Lünemann JD, Wiendl H, Klotz L, Schwab N.   +8 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

TRBC1/TRBC2 Immunophenotyping Provides Added Value During the Diagnostic Workup of T-Cell Lymphoma. [PDF]

EJHaem
Taylor J, Lakum T, Bevan S, Freeman T, Boot J, Bigogno CM, Raine J, Hookway E, Medani H, Calaminici M, Okosun J, Grantham M, Araf S, Smith M, Butler T, Farren T.   +15 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source