Results 11 to 20 of about 29,987 (218)

Inverse relationship between neoantigen clonality and T-cell activity reveals distinct immune phenotypes in HNSCC [PDF]

Journal of Translational Medicine
Background Neoantigens derived from tumour-specific mutations are critical targets for T-cell recognition, yet the relationship between neoantigen clonality and immune response in head and neck squamous cell carcinoma (HNSCC) remains poorly understood ...
Babak Saravi, Daman Deep Singh, Lara Schorn, Julian Lommen, Felix Schrader, Max Wilkat, Andreas Vollmer, Michael Vollmer, Stefan Hartmann, Marius Hörner, Kaustubh Adhikari, Elisabeth Roider, Jakob Wollborn, Norbert Kübler, Christoph Sproll   +14 more
doaj   +2 more sources

Genetic Diversity of Actinobacillus pleuropneumoniae Serovars in Hungary

Veterinary Sciences, 2022
A total of 114 Actinobacillus pleuropneumoniae isolates from porcine hemorrhagic necrotic pleuropneumonia were characterized by the examination of biotype, serovar, antibiotic resistance genes, and genes of toxin production.
Gábor Kardos, Rita Sárközi, Levente Laczkó, Szilvia Marton, László Makrai, Krisztián Bányai, László Fodor   +6 more
doaj   +1 more source

What Is behind the Correlation Analysis of Diarrheagenic E. coli Pathotypes?

Biology, 2022
The treatment failure recorded among patients and animals infected with diarrheagenic Escherichia coli (DEC) was increased due to the presence of specific virulence markers among these strains.
Mahmoud M. Bendary, Marwa I. Abd El-Hamid, Majid Alhomrani, Abdulhakeem S. Alamri, Rana Elshimy, Rasha A. Mosbah, Mosa M. Bahnass, Nasreen N. Omar, Mohammad M. Al-Sanea, Arwa R. Elmanakhly, Nesreen A. Safwat, Walaa A. Alshareef   +11 more
doaj   +1 more source

Impact of CMV Infection on Natural Killer Cell Clonal Repertoire in CMV-Naïve Rhesus Macaques

Frontiers in Immunology, 2019
Recent functional, gene expression, and epigenetic studies have suggested the presence of a subset of mature natural killer (NK) cells responsible for maintaining NK cell memory. The lack of endogenous clonal markers in NK cells impedes understanding the
Lauren L. Truitt, Di Yang, Di Yang, Diego A. Espinoza, Diego A. Espinoza, Xing Fan, Daniel R. Ram, Matilda J. Moström, Dollnovan Tran, Lesli M. Sprehe, R. Keith Reeves, R. Keith Reeves, Robert E. Donahue, Amitinder Kaur, Cynthia E. Dunbar, Chuanfeng Wu   +15 more
doaj   +1 more source

Coexistence of Multiple Endemic and Pandemic Lineages of the Rice Blast Pathogen

mBio, 2018
The rice blast fungus Magnaporthe oryzae (syn., Pyricularia oryzae) is both a threat to global food security and a model for plant pathology. Molecular pathologists need an accurate understanding of the origins and line of descent of M.
Pierre Gladieux, Sébastien Ravel, Adrien Rieux, Sandrine Cros-Arteil, Henri Adreit, Joëlle Milazzo, Maud Thierry, Elisabeth Fournier, Ryohei Terauchi, Didier Tharreau   +9 more
doaj   +1 more source

The role of anthropogenic dispersal in shaping the distribution and genetic composition of a widespread North American tree species

Ecology and Evolution, 2021
Dispersal and colonization are among the most important ecological processes for species persistence as they allow species to track changing environmental conditions.
Graham E. Wyatt, J. L. Hamrick, Dorset W. Trapnell   +2 more
doaj   +1 more source

Characterisation of Campylobacter spp. Isolated from Poultry in KwaZulu-Natal, South Africa

Antibiotics, 2020
This study investigated the antibiotic resistance, virulence profiles, and clonality of Campylobacter jejuni and Campylobacter coli isolated from an intensive poultry farming system in KwaZulu-Natal, South Africa. Following ethical approval, samples were
Stephanie Pillay, Daniel G. Amoako, Akebe L. K. Abia, Anou M. Somboro, Christiana O. Shobo, Keith Perrett, Linda A. Bester, Sabiha Y. Essack   +7 more
doaj   +1 more source

Histopathologic, phenotypic, and molecular criteria to discriminate low‐grade intestinal T‐cell lymphoma in cats from lymphoplasmacytic enteritis

Journal of Veterinary Internal Medicine, 2021
Background Differentiation of low‐grade intestinal T‐cell lymphoma (LGITL) from lymphoplasmacytic enteritis (LPE) in cats is a diagnostic challenge for pathologists.
Valérie Freiche, Mathieu V. Paulin, Nathalie Cordonnier, Hélène Huet, Maria‐Elena Turba, Elizabeth Macintyre, Thierry‐Jo Molina, Olivier Hermine, Lucile Couronné, Julie Bruneau   +9 more
doaj   +1 more source

A Persisting Nontropical Focus of Burkholderia pseudomallei with Limited Genome Evolution over Five Decades

mSystems, 2020
Burkholderia pseudomallei is the causative agent of the high-mortality disease melioidosis. Although melioidosis is classified as a tropical disease, rare autochthonous cases have been reported from temperate climatic regions, with uncertainty as to ...
Jessica R. Webb, Nicky Buller, Audrey Rachlin, Clayton Golledge, Derek S. Sarovich, Erin P. Price, Mark Mayo, Bart J. Currie   +7 more
doaj   +1 more source

Conservation Genetics of the Endangered Lompoc Yerba Santa (Eriodictyon capitatum Eastw., Namaceae), including Phylogenomic Insights into the Evolution of Eriodictyon

Plants, 2023
Eriodictyon capitatum (Namaceae) is a narrowly distributed shrub endemic to western Santa Barbara County, where it is known from only 10 extant California Natural Diversity Database element occurrences (EOs).
C. Matt Guilliams, Kristen E. Hasenstab-Lehman   +1 more
doaj   +1 more source