Results 251 to 260 of about 55,715 (309)

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Tumour-intrinsic features shape T cell differentiation through precursor to symptomatic multiple myeloma. [PDF]

Nat Commun
Foster KA, Rees E, Ainley L, Laidler A, Boyle EM, Lee L, Ward G, Galas-Filipowicz D, Fitzsimons E, Mikolajczak A, Lyon EJ, Jankovic D, Rahman J, Turakhia M, Mehta D, Garrod-Ketchley C, Uddin I, Beattie G, Hoade Y, Zhu C, Reading JL, Walker I, Chapman M, Ramasamy K, Herrero J, Chain B, Quezada SA, Yong KL.   +27 more
europepmc   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Tumour immune contexture and immune evasion in sporadic and Lynch syndrome-associated microsatellite unstable colorectal cancers. [PDF]

Br J Cancer
Martin S, Elomaa H, Väyrynen JP, Ahtiainen M, Wirta EV, Böhm J, Seppälä TT, Ristimäki A, Tahkola K, Mattila A, Koskensalo S, Renkonen-Sinisalo L, Lepistö A, Mecklin JP, Palin K, Rajamäki K, Aaltonen LA.   +16 more
europepmc   +1 more source

Effects of Vemurafenib ± Cobimetinib on Intratumoral and Host Immunity in Patients With BRAFV600 Mutant Melanoma: Implications for Combination With Immunotherapy. [PDF]

Cancer Med
Rapisuwon S, Slingluff CL, Wargo JA, Sullivan RJ, Izar B, Lin JR, Mauldin IS, Olson WC, Tran CA, Schwartzman GH, Gibney GT, Al-Refaie W, Atkins MB.   +12 more
europepmc   +1 more source

Antigen-specific T_H17 cells offset the age-related decline in durable T cell immunity. [PDF]

Sci Adv
Sturmlechner I, Jain A, Jiang J, Okuyama H, Mu Y, Own M, Weyand CM, Goronzy JJ.   +7 more
europepmc   +1 more source

Non-gastric mucosa-associated lymphoid tissue lymphomas: a narrative review of pathogenesis, diagnosis, and treatment strategies. [PDF]

Ann Transl Med
Mallick H, Karri V, Dalia S.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Central tolerance: Clonal deletion or clonal arrest?

European Journal of Immunology, 1994
AbstractStudies in various experimental animals have shown that developing T cells with specificity for self antigens can be prevented from maturation at an early stage of development. While several in vitro and in vivo experiments have shown that the mechanism of silencing autospecific T cells is the deletion of immature CD4+8+ thymocytes other ...
W, Swat, H, von Boehmer, P, Kisielow
openaire   +2 more sources