The Population Genetics of Clonal and Partially Clonal Diploids [PDF]
Genetics, 2003 Abstract The consequences of variable rates of clonal reproduction on the population genetics of neutral markers are explored in diploid organisms within a subdivided population (island model). We use both analytical and stochastic simulation approaches. High rates of clonal reproduction will positively affect heterozygosity.
Balloux, F. +2 more
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Impact of CMV Infection on Natural Killer Cell Clonal Repertoire in CMV-Naïve Rhesus Macaques
Frontiers in Immunology, 2019 Recent functional, gene expression, and epigenetic studies have suggested the presence of a subset of mature natural killer (NK) cells responsible for maintaining NK cell memory. The lack of endogenous clonal markers in NK cells impedes understanding the
Lauren L. Truitt +15 more
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Microsatellites within the feline androgen receptor are suitable for X chromosome-linked clonality testing in archival material [PDF]
, 2016 Objectives A hallmark of neoplasms is their origin from a single cell; that is, clonality. Many techniques have been developed in human medicine to utilise this feature of tumours for diagnostic purposes.
Farwick, Nadine M. +3 more
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Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy [PDF]
, 1984 Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts ...
Atchison, RW +12 more
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Combination immunotherapy induces distinct T-cell repertoire responses when administered to patients with different malignancies. [PDF]
, 2020 BackgroundCTLA-4 blockade with ipilimumab is Food and Drug Administration-approved for melanoma as a monotherapy and has been shown to modulate the circulating T-cell repertoire.
Cham, Jason +7 more
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IGHV mutational status of nodal marginal zone lymphoma by NGS reveals distinct pathogenic pathways with different prognostic implications [PDF]
, 2019 The precise B cell of origin and molecular pathogenesis of nodal marginal zone lymphoma (NMZL) remain poorly defined. To date, due to the rarity of NMZL, the vast majority of already-published studies have been conducted on a limited number of samples ...
Amato, Teresa +15 more
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Statistical Tests for Clonality [PDF]
Biometrics, 2006 Summary Cancer investigators frequently conduct studies to examine tumor samples from pairs of apparently independent primary tumors with a view to determine whether they share a “clonal” origin. The genetic fingerprints of the tumors are compared using a panel of markers, often representing loss of heterozygosity (LOH) at distinct genetic loci.
Begg, Colin B. +2 more
openaire +2 more sources
Coexistence of Multiple Endemic and Pandemic Lineages of the Rice Blast Pathogen
mBio, 2018 The rice blast fungus Magnaporthe oryzae (syn., Pyricularia oryzae) is both a threat to global food security and a model for plant pathology. Molecular pathologists need an accurate understanding of the origins and line of descent of M.
Pierre Gladieux +9 more
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Ecology and Evolution, 2021 Dispersal and colonization are among the most important ecological processes for species persistence as they allow species to track changing environmental conditions.
Graham E. Wyatt +2 more
doaj +1 more source
Genetic Basis of Self-Incompatibility in the Lichen-Forming Fungus Lobaria pulmonaria and Skewed Frequency Distribution of Mating-Type Idiomorphs: Implications for Conservation [PDF]
, 2012 Fungal populations that reproduce sexually are likely to be genetically more diverse and have a higher adaptive potential than asexually reproducing populations.
Cornejo, Carolina +4 more
core +3 more sources