Results 141 to 150 of about 790,447 (335)
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Regulating DSC2 Expression Affects the Proliferation and Apoptosis of Prostate Cancer Cells
Cancer Management and Research, 2020 Feng Jiang,1 Pengfei Wu2 1Department of Urology, Shanghai Pudong New Area People’s Hospital, Shanghai 201200, People’s Republic of China; 2Department of Urology, Tenth People’s Hospital of Tongji University, Shanghai 200072, People ...
Jiang F, Wu P
doaj
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Acyl-CoA esters modulate intracellular Ca2+ handling by permeabilized clonal pancreatic beta-cells.
, 1992 Jude T. Deeney +4 more
openalex +1 more source
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment [PDF]
, 2018 Ryō Yamamoto +7 more
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
VIM-Polyp: Multimodal Colon Polyp Dataset with Video, Histopathology, and Protein Expression
Scientific DataThe dataset in this study includes 202 videos with a total of 422 minutes, reaching Kayseri City Hospital’s gastroenterology department as colonoscopy videos and 1903 microscopy images between 2019 and 2021. It includes 399 colonoscopy, microscopy images,
Refika Sultan Doğan +3 more
doaj +1 more source
Expression of Colony-Stimulating Factor-1 (CSF-1) Messenger RNA in Human Endometrial Glands during the Menstrual Cycle: Molecular Cloning of a Novel Transcript That Predicts a Cell Surface Form oF CSF-1 [PDF]
, 1991 S. Pampfer +3 more
openalex +1 more source