Results 71 to 80 of about 746,964 (209)

ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cells- derived motoneurons [PDF]

open access: yes, 2015
Patient-derived induced Pluripotent Stem Cells (iPSCs) provide an opportunity to study human diseases mainly in those cases where no suitable model systems are available.
Bozzoni, Irene   +9 more
core   +4 more sources

Oxidative Stress and Apoptosis Contributed to Nonylphenol-Induced Cell Damage in Mouse NCTC Clone 1469 Cells

open access: yesJournal of Chemistry, 2020
Nonylphenol (NP) is considered an environmental toxicant and endocrine-disrupting compound. The present study aimed to investigate the effects of NP on NCTC Clone 1469, nonparenchymal hepatocytes, and to study the molecular basis of NP-induced liver ...
Xiaozhen Liu   +7 more
doaj   +1 more source

High throughput sequencing in acute lymphoblastic leukemia reveals clonal architecture of central nervous system and bone marrow compartments [PDF]

open access: yes, 2017
No abstract ...
Adams, Stuart   +9 more
core   +3 more sources

Cloning and Expression of hGAD65 Gene in E. Coli BL21

open access: yesIndonesian Journal of Biotechnology, 2013
The aim of this study is to construct the hGAD65 gene and to identify the hGAD65 clone by using PCR & RFLP. The samples were derived from normal person & DM patient’s blood.
Rista Nikmatu Rohmah   +3 more
doaj   +1 more source

Clinical correlation and prognostic impact of cytogenetic clone size for myelodysplastic syndromes/neoplasm

open access: yesBlood Neoplasia
: Most myelodysplastic syndromes/neoplasms (MDS) risk stratification models dichotomize conventional cytogenetic abnormalities into present or absent, neglecting the prognostic impact of clone size (percentage of the total cells/metaphases harboring the ...
Zhuoer Xie   +13 more
doaj   +1 more source

HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus

open access: yesFrontiers in Microbiology, 2019
BackgroundHIV-1 proviruses can persist during ART in clonally-expanded populations of CD4+ T cells. To date, few examples of an expanded clones containing replication-competent proviruses exist, although it is suspected to be common.
Andrew Musick   +18 more
doaj   +1 more source

T-cell clones in immunoparasitology

open access: yesParasitology Today, 1988
Cell-mediated immunity (CMI) is important in many parasitic infections. Stimulation by parasite-specific antigens can induce clonal expansion of parasite-specific T-cells which may act by direct cytotoxic action or by indirect effects on other cells such as natural killer cells or antibody-producing B-cells (Box 1).
Baldwin, C.L.   +2 more
openaire   +3 more sources

Nitrogen removal and ammonia-oxidising bacteria in a vertical flow constructed wetland treating inorganic wastewater [PDF]

open access: yes, 2011
Nitrogen removal performance and the ammonia-oxidising bacterial (AOB) community were assessed in the batch loaded 1.3ha saturated surface vertical flow wetland at CSBP Ltd, a fertiliser and chemical manufacturer located in Kwinana, Western Australia ...
Dallas, S.   +4 more
core   +2 more sources

Green formulation of copper nanoparticles by Pistacia khinjuk leaf aqueous extract: Introducing a novel chemotherapeutic drug for the treatment of prostate cancer

open access: yesOpen Chemistry
Prostate cancer is a cancer prevalent form characterized by serious clinical symptoms. The discovery of a novel supplement or medication for prostate cancer within the realm of chemotherapeutic drugs holds significant value.
Wang Zhuoqun, Li Ming, Zhang Qi, Xu Lei
doaj   +1 more source

CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein [PDF]

open access: yes, 2018
The use of alternative promoters for the cell type-specific expression of a given mRNA/protein is a common cell strategy. NEMO is a scaffold protein required for canonical NF-κB signaling.
Babaei, Milad   +7 more
core   +1 more source

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