Results 241 to 250 of about 1,253,785 (311)

Novel African American Colorectal Cancer <i>MSH3</i> Variants Associate With Major Genomic Instability. [PDF]

Hum Mutat
Rashid M, Brim H, Teng S, Sobitan A, Cruz-Cosme R, Qiyi T, Koi M, Casazza K, Surtees JA, Carethers JM, Ashktorab H.   +10 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Clonal biases dictate availability of colonic cancer driver mutations for transformation. [PDF]

Nat Commun
Skoufou-Papoutsaki N, Kemp R, Adler S, Marks K, Girard AC, Mehmed S, Lourenço FC, Moutin EB, Ten Hoopen R, Morrissey E, Winton DJ, Tourigny DS.   +11 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Revisiting the Origins of Cutaneous T-Cell Lymphoma: A Progenitor-Based Model. [PDF]

Cancers (Basel)
Zhang Y, Sokol L.
europepmc   +1 more source

Comparative whole-genome analyses of articular chondrocytes and skin fibroblasts reveal distinct genome instability landscapes in mesenchymal cell types. [PDF]

PLoS Genet
Sauty SM, Shine J, Bostan H, Li JL, Mieczkowski PA, Loeser RF, Diekman BO, Gordenin DA.   +7 more
europepmc   +1 more source

Revisiting viral reprogramming: Measles virus as a robust platform for high-quality iPSC generation. [PDF]

Mol Ther Adv
Moutaoufik MT, Chahine M.
europepmc   +1 more source

Prognostic significance of PNH clones in aplastic anemia treated with immunosuppression or allogeneic HSCT: a 20-year single-center experience. [PDF]

Blood Res
Haroon A, Alzahrani H, Saleh MFM, Aalahmari A, Alotaibi S, Elhassan T, Alfraih F, Alsharif F, Ahmed SO, Almohareb F, Fakih RE, Aljurf M.   +11 more
europepmc   +1 more source

Stability analysis of cocoa clones for yield in the humid tropics of India. [PDF]

Front Plant Sci
Kireeti A, Ramanandam G, Rao VG, Neeraja B, Rao NBVC, Apshara E, Sumitha S, Jerard AB.   +7 more
europepmc   +1 more source