Within-host co-evolution of KPC variants: plasmid-mediated dissemination of <i>bla</i><sub>Kpc-194</sub> and <i>bla</i><sub>Kpc-33</sub> in ST11-KL64 hypervirulent <i>Klebsiella pneumoniae</i> driving ceftazidime-avibactam resistance. [PDF]
Ding L +8 more
europepmc +1 more source
Shaping Ti3C2 MXene Nanospheres for Precision Near‐Infrared Photothermal Therapy
In this study, we report producing spherical MXenes via fs laser fragmentation of Ti3C2 flakes in liquid medium. The nanoparticles demonstrated pronounced light absorption and high photothermal conversion efficiencies of 68% and 63% under heating with NIR‐I and NIR‐II lasers, respectively.
Julia S. Babkova +21 more
wiley +1 more source
Progress in Molecular Plant Science (2023-2025). [PDF]
Chu Z.
europepmc +1 more source
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian +5 more
wiley +1 more source
InSillyClo, a User-Friendly Web Application to Assist Large-Scale Golden Gate Cloning and MoClo Workflows. [PDF]
Galez H +5 more
europepmc +1 more source
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat +11 more
wiley +1 more source
Immunoinformatic-driven design of a multi-epitope vaccine against <i>Helicobacter</i> <i>pylori</i>. [PDF]
Rahimi-Farsi N +6 more
europepmc +1 more source
An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee +4 more
wiley +1 more source
Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar +5 more
wiley +1 more source
Characterization of the novel class A β-Lactamase gene bla<sub>KOB-1</sub> in an Enterobacter isolate. [PDF]
Zhao J +9 more
europepmc +1 more source

