Results 301 to 310 of about 1,771,671 (365)

Designing a potent multivalent epitope vaccine candidate against Orientia tsutsugamushi via reverse vaccinology technique - bioinformatics and immunoinformatic approach. [PDF]

Front Immunol
Panda S, Swain SK, Sahu BP, Mahapatra SR, Dey J, Sarangi R, Ranade AV, Mishra N.   +7 more
europepmc   +1 more source

When Did I Begin? Another Critical Response to Norman Ford [PDF]

, 1991
Flaman, Paul
core   +1 more source

Discovery and Biosynthesis of Celluxanthenes, Antibacterial Arylpolyene Alkaloids From Diverse Cellulose‐Degrading Anaerobic Bacteria

Angewandte Chemie, EarlyView.
The structure and biosynthetic origin of the enigmatic “yellow affinity substance” (YAS) from the anaerobe thermophile Clostridium thermocellum (now: Acetivibrio thermocellus) were elucidated. YAS is a complex of unusual antibacterial arylpolyene alkaloids (celluxanthenes) that are produced by various cellulolytic anaerobes.
Keishi Ishida, Jana Krabbe, Philippe R. Meisinger, Gulimila Shabuer, Sebastian Schieferdecker, Michael Cyrulies, Cedric Tank, Emma Barnes, Christian Paetz, Christian Hertweck   +9 more
wiley   +1 more source

Hi-TARGET: a fast, efficient and versatile CRISPR type I-B genome editing tool for the thermophilic acetogen Thermoanaerobacter kivui. [PDF]

Biotechnol Biofuels Bioprod
Sitara A, Hocq R, Lu AJ, Pflügl S.
europepmc   +1 more source

Structural Basis of Sequential Enantioselective Epoxidation by a Flavin‐Dependent Monooxygenase in Lasalocid A Biosynthesis

Angewandte Chemie, EarlyView.
Lsd18 is a flavin‐dependent monooxygenase from Streptomyces lasalocidi that performs two enantioselective epoxidations during lasalocid A biosynthesis. X‐ray crystal structures of Lsd18 bound to a substrate and product analogue illuminate how this enzyme performs multiple epoxidations on the same substrate molecule and how it controls stereoselectivity.
Qian Wang, Yaming Deng, Dayan Viera, Xiaopeng Liu, Ning Liu, Yulu Hu, Xiangdong Hu, Hao Wei, Quan Zhou, Ting Lan, Wei He, Xi Chen, Chu‐Young Kim   +12 more
wiley   +1 more source

CryptKeeper: a negative design tool for reducing unintentional gene expression in bacteria. [PDF]

Synth Biol (Oxf)
Roots CT, Barrick JE.
europepmc   +1 more source

Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota

Angewandte Chemie, EarlyView.
Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog, Keishi Ishida, Kirstin Scherlach, Xiuqiang Chen, Benjamin Bartels, Sarah P. Niehs, Bachar Cheaib, Gianni Panagiotou, Christian Hertweck   +8 more
wiley   +1 more source

Utilizing the subtractive proteomics approach to design ensemble vaccine against Candida lusitaniae for immune response stimulation; a bioinformatics study. [PDF]

PLoS One
Naz H, Timotheous R, Sarwar MF, Nadeem T, Awan MF, Ali S, Awais S, Ahmed I.   +7 more
europepmc   +1 more source

Towards the first synthetic eukaryotic cell. [PDF]

Biosaf Health
Xu W, Teng Y, Zhou S.
europepmc   +1 more source