Results 61 to 70 of about 1,845,886 (394)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Quantum cloning machines for equatorial qubits
, 2001 Quantum cloning machines for equatorial qubits are studied. For the case of 1 to 2 phase-covariant quantum cloning machine, we present the networks consisting of quantum gates to realize the quantum cloning transformations.
A. Peres +22 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Gene Cloning and Protein Expression of Koi Herpesvirus ORF25
Hayati Journal of Biosciences, 2016 Koi herpesvirus (KHV) caused significant morbidity and mortality in koi and common carp (Cyprinus carpio). Glycoprotein has been used for vaccine development as sub unit vaccine against many viruses. KHV ORF25 is one of koi herpesvirus genes which encode
Murwantoko +2 more
doaj +1 more source
Cloning by positive maps in von Neumann algebras [PDF]
, 2014 We investigate cloning in the general operator algebra framework in arbitrary dimension assuming only positivity instead of strong positivity of the cloning operation, generalizing thus results obtained so far under that stronger assumption.
A Łuczak +11 more
core +2 more sources
FEBS Letters, EarlyView.Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa +8 more
wiley +1 more source
Polylinguality and Transcultural Practices, 2019 The British-Japanese writer Kazuo Ishiguro was awarded the Nobel Prize for the anti-utopian novel “Do not let me go” in 2017. The authors of the article in the framework of ontological poetics consider the aesthetic advantages of the work, paying close ...
Zukhra A. Kuchukova, Liana B. Berberova
doaj +1 more source
, 2006 In probabilistic cloning with two auxiliary systems, we consider and compare three different protocols for the success probabilities of cloning. We show that, in certain circumstances, it may increase the success probability to add an auxiliary system to
Azuma +24 more
core +1 more source
Optimal N-to-M Cloning of Quantum Coherent States [PDF]
, 2000 The cloning of continuous quantum variables is analyzed based on the concept of Gaussian cloning machines, i.e., transformations that yield copies that are Gaussian mixtures centered on the state to be copied.
A. S. Holevo +22 more
core +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source