Results 51 to 60 of about 1,036,847 (254)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Easy method for six-fragment Golden Gate Assembly of modular vectors
Efficient cloning techniques are a requirement for synthetic biology. This study provides a simplified cloning method based on Golden Gate Assembly that can be used for rapid vector construction.
Ionut Adrian Cepleanu-Pascu +3 more
doaj +1 more source
No-Cloning Theorem on Quantum Logics
This paper discusses the no-cloning theorem in a logico-algebraic approach. In this approach, an orthoalgebra is considered as a general structure for propositions in a physical theory.
Bennett C. H. +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Background: Somatic cell nuclear transfer (SCNT) is a prominent technology that can preserve superior genetic traits of animals and expand the population in a short time.
Young-Bum Son +10 more
doaj +1 more source
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Improved Method of Detection Falsification Results the Digital Image in Conditions of Attacks [PDF]
The modern level of information technologies development has led to unheard ease embodiments hitherto unauthorized modifications of digital content. At the moment, very important question is the effective expert examination of authenticity of digital ...
Kobozeva A.A., Grigorenko S.N.
doaj
Weak cloning of an unknown quantum state
The impossibility to clone an unknown quantum state is a powerful principle to understand the nature of quantum mechanics, especially within the context of quantum computing and quantum information.
Aharonov +12 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

