Lessons Learned from Somatic Cell Nuclear Transfer. [PDF]
Int J Mol Sci, 2020 Somatic cell nuclear transfer (SCNT) has been an area of interest in the field of stem cell research and regenerative medicine for the past 20 years.
Gouveia C, Huyser C, Egli D, Pepper MS.
europepmc +8 more sources
Generation of genome-edited dogs by somatic cell nuclear transfer [PDF]
BMC Biotechnology, 2022 Background Canine cloning technology based on somatic cell nuclear transfer (SCNT) combined with genome-editing tools such as CRISPR-Cas9 can be used to correct pathogenic mutations in purebred dogs or to generate animal models of disease.
Dong-Ern Kim +6 more
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Derivation of Embryonic Stem Cells from an Endangered Cattle Breed via Somatic Cell Nuclear Transfer [PDF]
CellsEmbryonic stem cells represent a valuable germplasm resource with significant implications for breed conservation, development, and utilization. However, the scarcity of genetic resources in endangered species poses a fundamental constraint on obtaining ...
Shigang Gu +7 more
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Mouse somatic cell nuclear transfer: What has changed and remained unchanged in 25 years [PDF]
The Journal of Reproduction and Development, 2023 Somatic cell nuclear transfer (SCNT) is the only reproductive technology used to produce individuals from somatic cells by transferring them to enucleated oocytes.
Kimiko INOUE
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Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos [PDF]
Nature Communications, 2020 The organisation of chromatin in somatic cell nuclear transfer (SCNT) embryos remains poorly understood. Here, the authors examine higher order chromatin structures of mouse SCNT embryos and provide insights into chromatin architecture reorganisation ...
Mo Chen +13 more
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Reproductive ability of minipigs as surrogates for somatic cell nuclear transfer [PDF]
Journal of Animal Science and TechnologyPigs are genetically, anatomically, and physiologically similar to humans. Recently, pigs are in the spotlight as a suitable source animal for xenotransplantation.
Joonho Moon +5 more
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Lysophosphatidic acid improves development of porcine somatic cell nuclear transfer embryos [PDF]
Journal of Animal Science and TechnologyThis study was conducted to investigate whether lysophosphatidic acid (LPA) could improve the development of porcine somatic cell nuclear transfer (SCNT) embryos.
Ling Sun +5 more
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Strategies to Improve the Efficiency of Somatic Cell Nuclear Transfer. [PDF]
Int J Mol Sci, 2022 Srirattana K, Kaneda M, Parnpai R.
europepmc +2 more sources
Veterinary Sciences, 2022 Cloning, commonly referred to as somatic cell nuclear transfer (SCNT), is the technique of enucleating an oocyte and injecting a somatic cell into it. This study was carried out with interspecific SCNT technology to clone the Arabian Oryx utilizing the ...
Aiman A. Ammari +4 more
doaj +1 more source
Haploidy of somatic cells in mouse oocyte using somatic cell nuclear transfer
Journal of Animal Reproduction and Biotechnology, 2022 Haploidization in somatic cells is the process of reducing the diploid somatic chromosomes to haploid. Several studies have attempted somatic haploidization using oocytes in mice and humans.
Yeonmi Lee , Eunju Kang
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