Results 31 to 40 of about 8,684,016 (282)
BMC Genomics, 2018 Background Nuclear reprogramming reinstates totipotency or pluripotency in somatic cells by changing their gene transcription profile. This technology is widely used in medicine, animal husbandry and other industries.
Yong Liu +13 more
doaj +1 more source
Nuclear reprogramming: kinetics of cell cycle and metabolic progression as determinants of success [PDF]
, 2012 Establishment of totipotency after somatic cell nuclear transfer (NT) requires not only reprogramming of gene expression, but also conversion of the cell cycle from quiescence to the precisely timed sequence of embryonic cleavage.
Franchesca Dawn Houghton (171722) +44 more
core +2 more sources
Influences of somatic donor cell sex on and embryo development following somatic cell nuclear transfer in pigs [PDF]
Asian-Australasian Journal of Animal Sciences, 2017 Objective The present study investigates pre- and post-implantation developmental competence of nuclear-transferred porcine embryos derived from male and female fetal fibroblasts.
Jae-Gyu Yoo +9 more
doaj +1 more source
Biotechnological bases of the development of cloned pig embryos
Вавиловский журнал генетики и селекции, 2019 The term ‘clone’ in animal biotechnology refers to an organism derived from non-sexual reproduction, which is both a direct offspring and a genetic copy of the parent organism.
A. V. Lopukhov +2 more
doaj +1 more source
Somatic Cell Nuclear Transfer Using Freeze-Dried Protaminized Donor Nuclei
, 2023 Somatic cell nuclear transfer (SCNT) is the only nuclear reprogramming method that allows rewinding an adult nucleus into a totipotent state. As such, it offers excellent opportunities for the multiplication of elite genotypes or endangered animals ...
Loi, Pasqualino +3 more
core +1 more source
Italian Journal of Animal Science, 2010 This study was conducted to evaluate the timing of cleavage and blastocoel formation of in vitro fertilized and nuclear transfer embryos and to compare the efficiency of in vitro fertilization (IVF) and somatic cell nuclear transfer (SCNT) techniques in ...
L.C. Cruz +5 more
doaj +1 more source
Interspecies Somatic Cell Nuclear Transfer: Advancements and Problems [PDF]
Cellular Reprogramming, 2013 Embryologists working with livestock species were the pioneers in the field of reprogramming by somatic cell nuclear transfer (SCNT). Without the "Dolly experiment," the field of cellular reprogramming would have been slow and induced plutipotent cells (iPSCs) would not have been conceived.
Lagutina, I. +3 more
openaire +3 more sources
Epigenetic manipulation to improve mouse SCNT embryonic development
Frontiers in Genetics, 2022 Cloned mammals can be achieved through somatic cell nuclear transfer (SCNT), which involves reprogramming of differentiated somatic cells into a totipotent state. However, low cloning efficiency hampers its application severely.
Yamei Li +5 more
doaj +1 more source
Nuclear reprogramming by somatic cell nuclear transfer – the cattle story [PDF]
Reproduction in Domestic Ruminants, 2007 Somatic cell nuclear transfer (cloning) returns a differentiated cell to a totipotent status; a process termed nuclear reprogramming. Nuclear transfer has potential applications in agriculture and biomedicine, but is limited by low efficiency. To understand the deficiencies of nuclear reprogramming, our research has focused on both candidate genes ...
X C, Tian +9 more
openaire +2 more sources
Functional consequences of mitochondrial mismatch in reconstituted embryos and offspring
The Journal of Reproduction and Development, 2019 Animal cloning technology has been developed to produce progenies genetically identical to a given donor cell. However, in nuclear transfer protocols, the recipient oocytes contribute a heritable mitochondrial genomic (mtDNA) background to the progeny ...
Kumiko TAKEDA
doaj +1 more source