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Somatic Cell Nuclear Transfer [PDF]

open access: yesNature, 2002
SOMATIC CELL NUCLEAR TRANSFER Somatic Cell Nuclear Transfer (419) (-
Wilmut, I. N. Beaujean P.A. de Sousa A. Dinnyes T.J. King L.A. Paterson D.N. Wells L.E. Young
core   +11 more sources

Somatic cell nuclear transfer

open access: yesAustralian Journal of Experimental Agriculture, 2004
Nuclear transfer research became front-page news when the birth of Dolly, the cloned ewe, was reported by Ian Wilmut and Keith Campbell in 1997. Since Dolly's birth, offspring from many other species have been produced using somatic cell nuclear transfer.
Hill,
core   +5 more sources

Telomere Elongation and Naive Pluripotent Stem Cells Achieved from Telomerase Haplo-Insufficient Cells by Somatic Cell Nuclear Transfer

open access: yesCell Reports, 2014
Summary: Haplo-insufficiency of telomerase genes in humans leads to telomere syndromes such as dyskeratosis congenital and idiopathic pulmonary fibrosis.
Li-Ying Sung   +16 more
doaj   +2 more sources

Embryonic Development following Somatic Cell Nuclear Transfer Impeded by Persisting Histone Methylation [PDF]

open access: yesCell, 2014
Mammalian oocytes can reprogram somatic cells into a totipotent state enabling animal cloning through somatic cell nuclear transfer (SCNT). However, the majority of SCNT embryos fail to develop to term due to undefined reprogramming defects.
Shogo Matoba, Yuting Liu, Falong Lu
exaly   +2 more sources

Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer

open access: yesCell, 2013
SummaryReprogramming somatic cells into pluripotent embryonic stem cells (ESCs) by somatic cell nuclear transfer (SCNT) has been envisioned as an approach for generating patient-matched nuclear transfer (NT)-ESCs for studies of disease mechanisms and for
Paula Amato   +2 more
exaly   +2 more sources

Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells

open access: yesCell Stem Cell, 2015
SummaryThe extremely low efficiency of human embryonic stem cell (hESC) derivation using somatic cell nuclear transfer (SCNT) limits its potential application.
Shogo Matoba, Yuting Liu, Falong Lu
exaly   +2 more sources

Production of Goats by Somatic Cell Nuclear Transfer

open access: yesNature Biotechnology, 1999
PRODUCTION OF GOATS BY SOMATIC CELL NUCLEAR TRANSFER Production of Goats by Somatic Cell Nuclear Transfer (17) (-
Baguisi, Alexander Esmail Behboodi David T. Melican Julie S. Pollock Margaret M. Destrempes Christine Cammuso Jennifer L. Williams Scott D. Nims Catherine A. Porter Patricia Midura Monica J. Palacios Sandra L. Ayres Richard S. Denniston Michael L. Hayes Carol A. Ziomek Harry M. Meade Robert A. Godke William G. Gavin Eric W. Overstrom Yann Echelard
core   +3 more sources

H3K4 Methylation-Dependent Memory of Somatic Cell Identity Inhibits Reprogramming and Development of Nuclear Transfer Embryos

open access: yesCell Stem Cell, 2017
Vertebrate eggs can induce the nuclear reprogramming of somatic cells to enable production of cloned animals. Nuclear reprogramming is relatively inefficient, and the development of the resultant embryos is frequently compromised, in part due to the ...
Eva Hörmanseder   +2 more
exaly   +3 more sources

Asymmetric nuclear reprogramming in somatic cell nuclear transfer? [PDF]

open access: yesBioEssays, 2008
International audienceDespite the progress achieved over the last decade after the birth of the first cloned mammal, the efficiency of reproductive cloning remains invariably low. However, research aiming at the use of nuclear transfer for the production
Loi, Pasqualino   +4 more
core   +6 more sources

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