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Somatic Cell Nuclear Transfer [PDF]
SOMATIC CELL NUCLEAR TRANSFER Somatic Cell Nuclear Transfer (419) (-
Wilmut, I. N. Beaujean P.A. de Sousa A. Dinnyes T.J. King L.A. Paterson D.N. Wells L.E. Young
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Nuclear transfer research became front-page news when the birth of Dolly, the cloned ewe, was reported by Ian Wilmut and Keith Campbell in 1997. Since Dolly's birth, offspring from many other species have been produced using somatic cell nuclear transfer.
Hill,
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Interspecies somatic cell nuclear transfer is dependent on compatible mitochondrial DNA and reprogramming factors. [PDF]
Interspecies somatic cell nuclear transfer (iSCNT) involves the transfer of a nucleus or cell from one species into the cytoplasm of an enucleated oocyte from another.
Yan Jiang +6 more
doaj +3 more sources
Cloning animals by somatic cell nuclear transfer – biological factors [PDF]
Cloning by nuclear transfer using mammalian somatic cells has enormous potential application. However, somatic cloning has been inefficient in all species in which live clones have been produced.
Enright Brian +3 more
doaj +3 more sources
Generation of bovine transgenics using somatic cell nuclear transfer [PDF]
The ability to produce transgenic animals through the introduction of exogenous DNA has existed for many years. However, past methods available to generate transgenic animals, such as pronuclear microinjection or the use of embryonic stem cells, have ...
Stice Steven L, Hodges Craig A
doaj +2 more sources
Production of Goats by Somatic Cell Nuclear Transfer
PRODUCTION OF GOATS BY SOMATIC CELL NUCLEAR TRANSFER Production of Goats by Somatic Cell Nuclear Transfer (17) (-
Baguisi, Alexander Esmail Behboodi David T. Melican Julie S. Pollock Margaret M. Destrempes Christine Cammuso Jennifer L. Williams Scott D. Nims Catherine A. Porter Patricia Midura Monica J. Palacios Sandra L. Ayres Richard S. Denniston Michael L. Hayes Carol A. Ziomek Harry M. Meade Robert A. Godke William G. Gavin Eric W. Overstrom Yann Echelard
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Asymmetric nuclear reprogramming in somatic cell nuclear transfer? [PDF]
Despite the progress achieved over the last decade after the birth of the first cloned mammal, the efficiency of reproductive cloning remains invariably low.
KHOCHBIN S +4 more
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Summary: Haplo-insufficiency of telomerase genes in humans leads to telomere syndromes such as dyskeratosis congenital and idiopathic pulmonary fibrosis.
Li-Ying Sung +16 more
doaj +2 more sources
The influence of interspecies somatic cell nuclear transfer on epigenetic enzymes transcription in early embryos [PDF]
One of the main reason for the incorrect development of embryos derived from somatic cell nuclear transfer is caused by insufficient demethylation of injected somatic chromatin to a state comparable with an early embryonic nucleus.
Martin Morovic +8 more
doaj +1 more source
25th ANNIVERSARY OF CLONING BY SOMATIC-CELL NUCLEAR TRANSFER: Epigenetic abnormalities associated with somatic cell nuclear transfer [PDF]
Abstract Twenty-five years have passed since the birth of Dolly the sheep, the first mammalian clone produced by adult somatic cell nuclear transfer (SCNT). During that time, the main thrust of SCNT-related research has been the elucidation of SCNT-associated epigenetic abnormalities and their correction, with the aim of improving the
Atsuo, Ogura +2 more
openaire +2 more sources

