Results 41 to 50 of about 42,166 (286)
Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]
, 1999 Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Vassilieva, Svetlana G. +4 more
core +1 more source
Biotechnological bases of the development of cloned pig embryos
Вавиловский журнал генетики и селекции, 2019 The term ‘clone’ in animal biotechnology refers to an organism derived from non-sexual reproduction, which is both a direct offspring and a genetic copy of the parent organism.
A. V. Lopukhov +2 more
doaj +1 more source
Italian Journal of Animal Science, 2010 This study was conducted to evaluate the timing of cleavage and blastocoel formation of in vitro fertilized and nuclear transfer embryos and to compare the efficiency of in vitro fertilization (IVF) and somatic cell nuclear transfer (SCNT) techniques in ...
L.C. Cruz +5 more
doaj +1 more source
Interspecies Somatic Cell Nuclear Transfer: Advancements and Problems [PDF]
Cellular Reprogramming, 2013 Embryologists working with livestock species were the pioneers in the field of reprogramming by somatic cell nuclear transfer (SCNT). Without the "Dolly experiment," the field of cellular reprogramming would have been slow and induced plutipotent cells (iPSCs) would not have been conceived.
Lagutina, I. +3 more
openaire +3 more sources
Nuclear reprogramming by somatic cell nuclear transfer – the cattle story [PDF]
Reproduction in Domestic Ruminants, 2007 Somatic cell nuclear transfer (cloning) returns a differentiated cell to a totipotent status; a process termed nuclear reprogramming. Nuclear transfer has potential applications in agriculture and biomedicine, but is limited by low efficiency. To understand the deficiencies of nuclear reprogramming, our research has focused on both candidate genes ...
X C, Tian +9 more
openaire +2 more sources
Functional consequences of mitochondrial mismatch in reconstituted embryos and offspring
The Journal of Reproduction and Development, 2019 Animal cloning technology has been developed to produce progenies genetically identical to a given donor cell. However, in nuclear transfer protocols, the recipient oocytes contribute a heritable mitochondrial genomic (mtDNA) background to the progeny ...
Kumiko TAKEDA
doaj +1 more source
Somatic Cell Nuclear Transfer (Cloning) Efficiency [PDF]
, 2015 Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus ...
Paterson, LA, Wilmut, Ian
core +1 more source
Study on Embryo Transfer System for Production of Transgenic Pigs
Journal of Animal Reproduction and Biotechnology, 2015 In the last 10 years, porcine somatic cell nuclear transfer to generate transgenic pig has been performed tremendous development with introduction and knockout of many genes.
Seungwon Na +10 more
doaj +1 more source
Nuclear reprogramming: kinetics of cell cycle and metabolic progression as determinants of success
, 2012 Establishment of totipotency after somatic cell nuclear transfer (NT) requires not only reprogramming of gene expression, but also conversion of the cell cycle from quiescence to the precisely timed sequence of embryonic cleavage.
Franchesca Dawn Houghton (171722) +44 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source