Results 31 to 40 of about 630,776 (310)

Integrative analysis of swine infectious diseases in the context of xenotransplantation

open access: yesInternational Journal of Infectious Diseases
Background: The initiation of clinical pig xenotransplantation trials offers the prospect of alleviating global organ shortage. However, current knowledge of swine-derived microorganisms relevant to xenotransplantation remains fragmented due to the ...
Jiayu Li   +9 more
doaj   +1 more source

Molecular identification, characterization, and expression analysis of a serine protease inhibitor gene from cotton bollworm, Helicoverpa armigera (Lepidoptera: Noctuidae) [PDF]

open access: yesBrazilian Journal of Biology, 2020
Serine protease inhibitors (serpins), a superfamily of protease inhibitors, are known to be involved in several physiological processes, such as development, metamorphosis, and innate immunity.
Muhammad Shakeel
doaj   +1 more source

To clone or not to clone.

open access: yesJournal of Postgraduate Medicine, 2003
'There is perhaps no phenomenon in the field of biology that touches so many fundamental questions as the union of the germ cells in the act of fertilisation; in the supreme event all the strands of webs of two lives are gathered in one knot, from which they diverge again and are rewoven in a new individual life history.
openaire   +2 more sources

Birth of clones of the world’s first cloned dog [PDF]

open access: yesScientific Reports, 2017
AbstractAnimal cloning has gained popularity as a method to produce genetically identical animals or superior animals for research or industrial uses. However, the long-standing question of whether a cloned animal undergoes an accelerated aging process is yet to be answered. As a step towards answering this question, we compared longevity and health of
Kim, Min Jung   +8 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Cloning and gene expression of alkane hydroxylase gene from Pseudomonas putida [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2017
Pseudomonas putida is a bacterium that has ability to growth on limited substrates that mainly is alkanes. The ability to use wide range of hydrocarbons is advantage of this bacterium to other bacteria community. P. putida have alkane hydroxylase system (
Mahdi Hasanshahian, Hadi Ravan
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Molecular Cloning and Functional Characterization of a Salt Tolerance-Associated Gene IbNFU1 from Sweetpotato

open access: yesJournal of Integrative Agriculture, 2013
Iron-sulfur cluster biosynthesis involving the nitrogen fixation (Nif) proteins has been proposed as a general mechanism acting in various organisms. NifU-like protein may play an important role in protecting plants against abiotic and biotic stresses ...
Lian-jun WANG   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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