Results 31 to 40 of about 695,609 (307)
Polylinguality and Transcultural Practices, 2019 The British-Japanese writer Kazuo Ishiguro was awarded the Nobel Prize for the anti-utopian novel “Do not let me go” in 2017. The authors of the article in the framework of ontological poetics consider the aesthetic advantages of the work, paying close ...
Zukhra A. Kuchukova, Liana B. Berberova
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The First Genomic Analysis of Visna/Maedi Virus Isolates in China
Frontiers in Veterinary Science, 2022 Visna/Maedi virus (VMV) is a neglected pathogen that damages sheep and goats' nervous and respiratory systems. The virus was discovered 80 years ago and has been endemic in China for nearly four decades; nevertheless, there is little information ...
Jian-Yong Wu +6 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Environmental determinants of male infertility: emerging threats and technological interventions
Frontiers in MedicineMale infertility stands as a significant global concern, contributing to nearly 50% of infertility cases and affecting approximately 7% of the male population. Mounting evidence identifies environmental degradation is a major, modifiable driver. Numerous
P. Jagadesh, T. B. Sridharan
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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Toxicology ReportsExposure to air pollution poses significant risks to human health, including detrimental effects on the reproductive system, affecting both men and women.
Abilash D, Sridharan T B
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
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Ars Mathematica Contemporanea, 2014 Each finite graph on n vertices determines a special ( n − 1) -fold covering graph that we call the clone cover . Several equivalent definitions and basic properties about this remarkable construction are presented. In particular, we show that for k ≥ 2 , the clone cover of a k -connected graph is k -connected, the clone cover of a ...
Aleksander Malnic +2 more
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Spatial dynamics of mTOR pathway activity during bovine embryo development
Frontiers in Cell and Developmental BiologyThe mTOR pathway regulates cell proliferation, growth, survival, and metabolism by integrating nutritional and growth factor signaling. In embryos, its activity is influenced by the availability of nutrients in the culture medium, and it can affect the ...
Francieli P. Berling +4 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source