Results 91 to 100 of about 125,001 (364)

Steerable Delivery Sheath for Optimized LAA Closure: First Experience and Procedural Outcomes

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The new Amplatzer Steerable Delivery Sheath is a delivery system designed to improve ease‐of‐use and procedural results of left atrial appendage closure (LAAC). We aimed to compare procedural results after switching our LAAC program at a tertiary care center with the Amulet device to the Steerable Delivery Sheath, with a control ...
Matthias Mezger, Christina Paitazoglou, Christian Frerker, Thomas Stiermaier, Ingo Eitel   +4 more
wiley   +1 more source

An Idiosyncratic Reaction to Clopidogrel [PDF]

The Permanente Journal, 2015
Clopidogrel is an irreversible antiplatelet agent belonging to the thienopyridine group that acts to antagonize the adenosine diphosphate P2Y12 receptor on platelets. It thus inhibits the activation of platelet glycoprotein GPIIb/IIIa complex, which is essential for fibrinogen—platelet complex formation.
Kapila, Aaysha, Chhabra, Lovely, Locke, Allison Diane, Patel, Pranav, Khanna, Atul, Reddy, Chakradhar M., Young, Mark F.   +6 more
openaire   +4 more sources

INtravaScular OptIcal Frequency Domain ImaGing EvaluaTion of the Femoropopliteal Lesion With JETSTREAM Atherectomy (INSIGHT JETSTREAM)

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background There have been no prior reports of detailed evaluations using intravascular imaging during Jetstream treatment. Aims This study, therefore, aimed to investigate the effects of calcification characteristics and wire bias on lumen gain in Jetstream atherectomy using optical frequency domain imaging (OFDI). Methods This study enrolled
Koji Kuroda, Amane Kozuki, Kenzo Uzu, Takafumi Todoroki, Masamichi Iwasaki, Junichi Imanishi, Souichiro Yamashita, Wataru Fujimoto, Makoto Takemoto, Mayuka Masuda, Masanori Okuda   +10 more
wiley   +1 more source

Assessment of P2Y12 Inhibition by Clopidogrel in Feline Platelets Using Flow Cytometry Quantification of Vasodilator-Stimulated Phosphoprotein Phosphorylation

Frontiers in Veterinary Science, 2020
The primary objective of this study was to evaluate a novel flow cytometry-based assay of quantifying platelet phosphorylation of vasodilator-stimulated phosphoprotein (P-VASP) in cats that received clopidogrel treatment.
Ronald H. L. Li, Nghi Nguyen, Tommaso Rosati, Karl Jandrey   +3 more
doaj   +1 more source

Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]

, 2018
© The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast, AD Michelson, B Labarthe, B Shen, C Patrono, CT Ammollo, D Capodanno, D Gailani, DA Gorog, Diana A. Gorog, DM Coenen, E Álvarez, ER Bates, F Kabirian, F Müller, F Semeraro, G Stephens, H Brogren, HE Speich, HE Speich, HJ Weiss, HJ Weiss, HR Baumgartner, J Zilberman-Rudenko, JD McFadyen, JI Weitz, JM Cosemans, JP Collet, JP Collet, K Hosokawa, K Nagatsuka, KS Sakariassen, L Valerio, LF Brass, M Cattaneo, M Farag, M Humbert, M Larsson, M Li, M Ungerer, MA Bailey, MI Furman, MJ Price, ML Montfoort von, MS Sabatine, P Andre, P Seizer, PA Borne von dem, PP Wadowski, R Hellmuth, R Nergiz-Unal, RA Ajjan, S Goto, S Goto, SA Shaya, SB Larsen, SJ Marciniak, T Heitzer, T Renné, VT Turitto, VT Turitto, WA Schumacher, WS Nesbitt, X Wang, Y Yano, YC Lau, ZM Ruggeri   +66 more
core   +1 more source

Effect of clopidogrel added to aspirin in patients with atrial fibrillation.

New England Journal of Medicine, 2009
BACKGROUND Vitamin K antagonists reduce the risk of stroke in patients with atrial fibrillation but are considered unsuitable in many patients, who usually receive aspirin instead.
S. Connolly, J. Pogue, R. Hart, S. Hohnloser, M. Pfeffer, S. Chrolavicius, S. Yusuf   +6 more
semanticscholar   +1 more source

Impact of Diabetes on Long‐Term Outcomes of Percutaneous Coronary Intervention for Coronary Bifurcation Lesions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) is a well‐known risk factor for cardiovascular diseases, including coronary artery diseases (CAD). Complex percutaneous coronary intervention (PCI) such as PCI for bifurcation lesions often yields poor outcomes, especially in DM patients.
Subin Lim, Soon Jun Hong, Ju Hyeon Kim, Jung‐Joon Cha, Hyung Joon Joo, Jae Hyoung Park, Cheol Woong Yu, Do‐Sun Lim, Chang‐Wook Nam, the COBIS III investigators, Hyo‐Soo Kim, Woo Jung Chun, Seung‐Ho Hur, Seung Hwan Han, Seung‐Woon Rha, In‐Ho Chae, Jin‐Ok Jeong, Jung Ho Heo, Junghan Yoon, Ki Hong Choi, Young Bin Song, Hyeon‐Cheol Gwon, Jong‐Seon Park, Myeong‐Ki Hong, Joon‐Hyung Doh, Kwang Soo Cha, Doo‐Il Kim, Sang Yeub Lee, Kiyuk Chang, So‐Yeon Choi, Myung Ho Jeong, Bon‐Kwon Koo   +31 more
wiley   +1 more source

rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. [PDF]

, 2014
BackgroundBiologic sex can influence response to pharmacologic therapy. The purpose of this proof-of-concept study was to evaluate the medicating effects of estrogen in the efficacy of acute antiplatelet loading therapy on stroke outcome in the rabbit ...
Compton, M Peggy, Eastwood, Jo-Ann, Gylys, Karen, Meyer, Dawn M, Zivin, Justin A   +4 more
core   +3 more sources

Clinically Significant Bleeding With Ticagrelor Versus Clopidogrel in Korean Patients With Acute Coronary Syndromes Intended for Invasive Management: A Randomized Clinical Trial.

Circulation, 2019
Owing to the differential propensity for bleeding and ischemic events with response to antiplatelet therapy, the safety and effectiveness of potent P2Y12 inhibitor ticagrelor in East Asian populations remain uncertain.
Duk‐Woo Park, O. Kwon, Jae-Sik Jang, S. Yun, Hanbit Park, Do-Yoon Kang, Jung‐Min Ahn, P. Lee, Seung‐Whan Lee, Seong-Wook Park, Si-Wan Choi, Sang‐Gon Lee, H. Yoon, T. Ahn, Moo-Hyun Kim, D. Nah, S. Lee, J. Chae, Seung‐Jung Park   +18 more
semanticscholar   +1 more source

Safety and Efficacy of Single Femoral Vein Puncture Technique for Double Access in Patent Foramen Ovale Closure Under ICE Guidance—A Single Center Experience of the “Two‐In‐One Technique”

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background In selected patient populations, percutaneous closure of patent foramen ovale has been shown to be beneficial in preventing cerebral ischaemic events. In most cases, this procedure requires echocardiographic guidance, which may be transesophageal, transthoracic or intracardiac.
Pierre Guilleminot, Mathieu Mourot, Luc Lorgis, Romain Didier, Benjamin Ferrand, Gabriel Laurent, Catherine Vergely, Charles Guenancia, Thibaut Pommier   +8 more
wiley   +1 more source