Results 121 to 130 of about 178,738 (259)
Cardiology Research and Practice, 2013 Background. The CYP2C19*2 allele may be associated with a reduced antiplatelet effect for clopidogrel. Here, we assessed whether CYP2C19*2 alleles correlate with clopidogrel responsiveness following the administration of clopidogrel in healthy Malaysian ...
Yanti Nasyuhana Sani +6 more
doaj +1 more source
Population Pharmacokinetics of Sildenafil in Dogs With Naturally Occurring Pulmonary Hypertension
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT The pharmacokinetics of sildenafil are ill‐defined in dogs with naturally occurring pulmonary hypertension (PH). Because the plasma concentrations of sildenafil have not been reported for dogs with this disease, this study aimed to describe the population pharmacokinetics of sildenafil in a sample of dogs with PH. Twenty client‐owned dogs with
Mariko Yata +3 more
wiley +1 more source
A Pilot Study of Value of Information Analysis to Support Research Recommendations for the National Institute for Health and Clinical Excellence [PDF]
Background - This project developed as a result of the activities of the Research Teams at the Centre for Health Economics, University of York, and ScHARR at the University of Sheffield in the methods and application of decision analysis and value of ...
Alan Wailoo +7 more
core
Prasugrel versus adjusted high-dose clopidogrel in patients with high-on- clopidogrel platelet reactivity: the PECS-HPR randomised, multicentre study [PDF]
, 2015 Aims: Repeated loading doses (LD) of clopidogrel were shown to effectively overcome high-on-clopidogrel platelet reactivity (HPR); however, comparison to potent P2Y12-inhibitors is lacking.
Aradi, Dániel
core
Early Mobilization After Pacemaker Implantation
Pacing and Clinical Electrophysiology, EarlyView.ABSTRACT Background The increasing use of cardiac implantable electronic devices (CIED) is leading to a rise in procedure‐related complications. Objective This trial aimed to assess the safety and feasibility of early mobilization and the possibility of same‐day discharge following permanent pacemaker implantation.
Jiří Šmíd +3 more
wiley +1 more source
Therapeutics and Clinical Risk Management, 2015 Zhi-Yu Wang,1 Meng Chen,1 Ling-Ling Zhu,2 Lu-Shan Yu,3 Su Zeng,3 Mei-Xiang Xiang,4 Quan Zhou1 1Department of Pharmacy, 2VIP Care Ward, Division of Nursing, the Second Affiliated Hospital, School of Medicine, 3Department of Pharmaceutical Analysis and ...
Wang ZY +6 more
doaj
Transplant Infectious Disease, EarlyView.This study comparing 4‐month rifampin with 9‐month isoniazid for latent tuberculosis in kidney transplant candidates showed higher treatment completion rates and no transaminase elevations in the rifampin group. However, some patients experienced an increase in blood pressure while taking antihypertensive medications known to interact with rifampin ...
Jacques Simkins +13 more
wiley +1 more source
Clopidogrel discontinuation and platelet reactivity following coronary stenting. [PDF]
, 2010 Aims: Antiplatelet therapy with aspirin and clopidogrel are recommended for 1 year after drug-eluting stent (DES) implantation or myocardial infarction. However, the discontinuation of antiplatelet therapy has become an important issue as recent studies ...
Dicker, Patrick +6 more
core +1 more source
Carotid artery dissection linked to intermittent apnoeic swimming: A case–control study
Experimental Physiology, EarlyView.Abstract Internal carotid artery (ICA) dissection is a rare and potentially devastating cause of cerebral ischaemia, initiated by an intimal tear or rupture of the vasa vasorum, that can lead to an intraluminal thrombus, vascular stenosis, occlusion, or dissecting aneurysm formation.
Damian M. Bailey +14 more
wiley +1 more source