Results 121 to 130 of about 89,659 (294)

Evaluating the impact of general practice pharmacist‐led person‐centred medicines reviews on medicines appropriateness and patient‐reported outcome measures

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to investigate the impact of pharmacist‐led person‐centred medicines reviews in general practices on medicines appropriateness, polypharmacy indicators (high‐risk prescribing markers), and patient‐reported outcome measures (PROMs).
Clare Kinahan, Ciara Kirke, Leon O'Hagan, Frank Moriarty, Kevin D. Murphy, Laura J. Sahm, Cian O'Mahony, Emma J. Coyle, Stephen Byrne, Kieran Dalton   +9 more
wiley   +1 more source

Time Course for Benefit and Risk of Clopidogrel and Aspirin after Acute Transient Ischemic Attack and Minor Ischemic Stroke: A Secondary Analysis from the POINT Randomized Trial.

Circulation, 2019
BACKGROUND In patients with acute minor ischemic stroke or high-risk transient ischemic attack enrolled in the POINT trial, the combination of clopidogrel and aspirin for 90 days reduced major ischemic events but increased major hemorrhage compared to ...
S. C. Johnston, J. Elm, J. D. Easton, M. Farrant, William G. Barsan, Anthony S Kim, Anne S. Lindblad, Yuko Y. Palesch, Karla G. Zurita, Gregory W. Albers, Brett L. Cucchiara, Dawn O. Kleindorfer, H. Lutsep, C. Pearson, Pramod Sethi, Nirali Vora   +15 more
semanticscholar   +1 more source

Concomitant use of clopidogrel and proton pump inhibitors: A retrospective analysis of prescription behaviour

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Since omeprazole and esomeprazole reduce the effect of clopidogrel on the inhibition of platelet aggregation, concomitant use of these drugs has been discouraged by the Food and Drug Administration (FDA) and European Medicines Agency (EMA) since 2010.
Sarah Wilkes, Kayleigh van de Wiel, Kelly Mulder, Hanne van Ballegooijen, Rianne Zaal, Hugo van der Kuy   +5 more
wiley   +1 more source

Abrupt Cessation of One-Year Clopidogrel Treatment Is Not Associated With Thrombotic Events

Journal of Pharmacological Sciences, 2011
.: We aimed to examine the rate of thrombotic events after discontinuation of one year clopidogrel therapy in patients with implanted coronary stent, and to determine platelet aggregability by multiple electrode analyzer after cessation of clopidogrel ...
Nina Djukanovic, Zoran Todorovic, Slobodan Obradovic, Danijela Zamaklar-Trifunovic, Srdjana Njegomirovic, Nataša M. Milic, Milica Prostran, Miodrag Ostojic   +7 more
doaj  

Omega-3 fatty acid ethyl esters do not improve clopidogrel associated P2Y12 inhibition in stroke patients

Neurology International, 2015
The specific action of omega-3 fatty acid ethyl esters (OFA) in preventing cerebrovascular disease remains unknown, but research has demonstrated multiple possible mechanisms.
Ping Li, Haris Kamal, Melissa Baxter, Bijal K. Mehta   +3 more
doaj   +1 more source

Genetic Polymorphisms and Clopidogrel Efficacy for Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis

Circulation, 2017
Background: The association of genetic polymorphisms and clopidogrel efficacy in patients with ischemic stroke or transient ischemic attack (TIA) remains controversial.
Yuesong Pan, Weiqi Chen, Yun Xu, X. Yi, Yan Han, Qingwu Yang, Xin Li, Lian Huang, S. Johnston, Xingquan Zhao, Liping Liu, Qi Zhang, Guangyao Wang, Yongjun Wang, Yilong Wang   +14 more
semanticscholar   +1 more source

Combination of rhinoshave and fractional ablative CO2 laser therapy for fine contouring of pronounced rhinophyma – A monocentric retrospective study with long‐term follow‐up

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Currently, there are no effective drug therapy options that lead to the regression of rhinophyma. Many surgical procedures for treating rhinophyma have been published; however, there are limited data on their effectiveness. In addition, these treatment options often lead to persistent hypopigmented scarring if excessive ablation or ...
Conrad Hempel, Anna‐Theresa Seitz, Viktor Schnabel, Till Mittank‐Weidner, Jan‐Christoph Simon, Sonja Grunewald   +5 more
wiley   +1 more source

Leveraging Federated Learning for Automatic Detection of Clopidogrel Treatment Failures [PDF]

arXiv
The effectiveness of clopidogrel, a widely used antiplatelet medication, varies significantly among individuals, necessitating the development of precise predictive models to optimize patient care. In this study, we leverage federated learning strategies to address clopidogrel treatment failure detection.
arxiv  

Clopidogrel-induced hepatotoxicity

Journal of Postgraduate Medicine, 2008
ollowing elective percutaneous coronary intervention (PCI), a 56-year-old man received clopidogrel 75 mg OD along with his long-term medication (> five years treatment with aspirin 75 mg OD and simvastatin 40 mg OD). Pre-PCI, his liver biochemistry (LFT’s) was normal.
Wiper, A, Schmitt, M, Roberts, DH
openaire   +3 more sources

Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches

PROTEOMICS, EarlyView.
Paul Perco, Matthias Ley, Kinga Kęska‐Izworska, Dorota Wojenska, Enrico Bono, Samuel M. Walter, Lucas Fillinger, Klaus Kratochwill   +7 more
wiley   +1 more source