Results 121 to 130 of about 169,996 (318)

Migraine and patent foramen ovale: correlation, coexistence, dependence. A narrative review

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary This review looked at what scientists know about the connection between migraine and a small heart opening called a patent foramen ovale (PFO). It showed that people with migraine, especially with aura, often have PFO, but it is not certain whether closing this heart opening helps prevent strokes in these patients.
Olga Grodzka   +5 more
wiley   +1 more source

The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial programme. Rationale, design and baseline characteristics including a meta-analysis of the effects of thienopyridines in vascular disease [PDF]

open access: bronze, 2000
Salim Yusuf   +97 more
openalex   +1 more source

Demographic, imaging and disease patterns of moyamoya angiopathy in South Auckland: an observational study from electronic health records

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Prior reports show the occurrence of moyamoya angiopathy in the ethnically diverse South Auckland region, but little is known about the sociodemographic burden of the condition and clinical outcomes. Aims To determine the disease prevalence, age, sex and ethnic distribution, management and patient outcomes in adults residing in ...
Karim Mahawish   +3 more
wiley   +1 more source

The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice

open access: yesiScience
Summary: Clopidogrel has been shown to play a protective role against diabetic nephropathy. However, whether clopidogrel exerts a protective effect against diabetic cardiomyopathy (DCM) is unknown.
Bing Li   +3 more
doaj   +1 more source

The CYP2C19*1/*2 Genotype Does Not Adequately Predict Clopidogrel Response in Healthy Malaysian Volunteers

open access: yesCardiology Research and Practice, 2013
Background. The CYP2C19*2 allele may be associated with a reduced antiplatelet effect for clopidogrel. Here, we assessed whether CYP2C19*2 alleles correlate with clopidogrel responsiveness following the administration of clopidogrel in healthy Malaysian ...
Yanti Nasyuhana Sani   +6 more
doaj   +1 more source

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

open access: yesJournal of the American Geriatrics Society, EarlyView.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao   +11 more
wiley   +1 more source

Clopidogrel resistance and its relevance: Current concepts

open access: yesJournal of Family Medicine and Primary Care
Clopidogrel is the most widely used P2Y12 receptor inhibitor (P2Y12i) as a part of dual antiplatelet therapy along with aspirin. Clopidogrel is a pro-drug and is metabolized to its active metabolite by the hepatic enzyme cytochrome P4502C19 (CYP2C19 ...
Akshyaya Pradhan   +3 more
doaj   +1 more source

Regular Medications Administered to Older Adults in Aged Care Facilities: A Retrospective Descriptive Study

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Aim(s) To explore which regularly prescribed medications are most commonly administered to older adults in aged care facilities in Australia, by whom and when, and to identify the prevalence of polypharmacy in this population group. Design Retrospective descriptive study.
Stephanie M. Garratt   +3 more
wiley   +1 more source

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