Results 51 to 60 of about 159,122 (291)

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

Massive close binaries II

open access: yes, 2003
In the present review we summarize direct and indirect evidence that the massive close binary frequency is very large. We then discuss the binary evolutionary processes and we present a general massive close binary evolutionary scheme.
Vanbeveren, Dany
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Short-period Heartbeat Binaries from TESS Full-frame Images

open access: yesThe Astrophysical Journal Supplement Series
We identify 240 short-period ( P ≲ 10 days) binary systems in Transiting Exoplanet Survey Satellite data, 180 of which are heartbeat binaries. The sample is mostly a mix of A- and B-type stars and primarily includes eclipsing systems, where over 30% of ...
Siddhant Solanki   +11 more
doaj   +1 more source

Orbital Decay in an Accreting and Eclipsing 13.7 Minute Orbital Period Binary with a Luminous Donor

open access: yesThe Astrophysical Journal Letters, 2023
We report the discovery of ZTF J0127+5258, a compact mass-transferring binary with an orbital period of 13.7 minutes. The system contains a white dwarf accretor, which likely originated as a post–common envelope carbon–oxygen (CO) white dwarf, and a warm
Kevin B. Burdge   +26 more
doaj   +1 more source

The Role of Multiplicity in Disk Evolution and Planet Formation [PDF]

open access: yes, 2011
The past decade has seen a revolution in our understanding of protoplanetary disk evolution and planet formation in single star systems. However, the majority of solar-type stars form in binary systems, so the impact of binary companions on ...
Hillenbrand, Lynne A.   +3 more
core   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

CW Cas: A Solar-type Contact Binary System with an Unseen Third Companion in a Hierarchical Quadruple System

open access: yesThe Astrophysical Journal
We present a comprehensive multiband photometric and spectroscopic study of the G-type binary CW Cas. Analysis of its double-lined spectroscopic radial velocity curves yields a reliable mass ratio of q  = 1.88(9).
Azizbek Matekov   +13 more
doaj   +1 more source

Detached white-dwarf close-binary stars -- CV's extended family [PDF]

open access: yes, 1999
I review detached binaries consisting of white dwarfs with either other white dwarfs or low mass main-sequence stars in tight orbits around them. Orbital periods have been measured for 15 white dwarf/white dwarf systems and 22 white dwarf/M dwarf systems.
Marsh, T. R.
core   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy