Results 61 to 70 of about 159,898 (288)
Evidence for Prolonged Main Sequence Stellar Evolution of F Stars in close binaries [PDF]
, 2001 Binary F stars exhibit large brightness anomaly, which is defined here as the difference between the absolute magnitude from the uvby photometry and the actual absolute magnitude of the star.
A. A. Suchkov +16 more
core +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2003 In the present review we summarize direct and indirect evidence that the massive close binary frequency is very large. We then discuss the binary evolutionary processes and we present a general massive close binary evolutionary scheme.
Vanbeveren, Dany
core +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Evolution of Mass Functions of Coeval Stars through Wind Mass Loss and Binary Interactions [PDF]
, 2015 Accurate determinations of stellar mass functions and ages of stellar populations are crucial to much of astrophysics. We analyse the evolution of stellar mass functions of coeval main sequence stars including all relevant aspects of single- and binary ...
de Mink, S. E. +3 more
core +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Hot Stars With Cool Companions [PDF]
, 2014 Young intermediate-mass stars have become high-priority targets for direct-imaging planet searches following the recent discoveries of planets orbiting e.g. HR 8799 and Beta Pictoris.
Dodson-Robinson, Sarah +2 more
core +3 more sources
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
The Mass-Radius(-Rotation?) Relation for Low-Mass Stars [PDF]
, 2010 The fundamental properties of low-mass stars are not as well understood as those of their more massive counterparts. The best method for constraining these properties, especially masses and radii, is to study eclipsing binary systems, but only a small ...
Adam L. Kraus +45 more
core +2 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source