Results 51 to 60 of about 159,898 (288)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Short-period Heartbeat Binaries from TESS Full-frame Images
The Astrophysical Journal Supplement SeriesWe identify 240 short-period ( P ≲ 10 days) binary systems in Transiting Exoplanet Survey Satellite data, 180 of which are heartbeat binaries. The sample is mostly a mix of A- and B-type stars and primarily includes eclipsing systems, where over 30% of ...
Siddhant Solanki +11 more
doaj +1 more source
Orbital Decay in an Accreting and Eclipsing 13.7 Minute Orbital Period Binary with a Luminous Donor
The Astrophysical Journal Letters, 2023 We report the discovery of ZTF J0127+5258, a compact mass-transferring binary with an orbital period of 13.7 minutes. The system contains a white dwarf accretor, which likely originated as a post–common envelope carbon–oxygen (CO) white dwarf, and a warm
Kevin B. Burdge +26 more
doaj +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
The Astrophysical JournalWe present a comprehensive multiband photometric and spectroscopic study of the G-type binary CW Cas. Analysis of its double-lined spectroscopic radial velocity curves yields a reliable mass ratio of q = 1.88(9).
Azizbek Matekov +13 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Detached white-dwarf close-binary stars -- CV's extended family [PDF]
, 1999 I review detached binaries consisting of white dwarfs with either other white dwarfs or low mass main-sequence stars in tight orbits around them. Orbital periods have been measured for 15 white dwarf/white dwarf systems and 22 white dwarf/M dwarf systems.
Marsh, T. R.
core +3 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Elliptical motions of stars in close binary systems
, 2010 Motions of stars in close binary systems with a conservative mass exchange are examined. It is shown that Paczynski-Huang model widely used now for obtaining the semi-major axis variation of a relative stars orbit is incorrect, because it brings about ...
A. Kruszevski +16 more
core +1 more source