Results 71 to 80 of about 159,543 (291)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The Eclipsing Novalike Cataclysmic Variable CRTS SSS100505 J093417-174421

The Astrophysical Journal
Time-resolved optical photometry, complemented by Transiting Exoplanet Survey Satellite (TESS) data and long-term survey light curves, reveals that the transient object CRTS SSS100505 J093417-174421 is an eclipsing novalike cataclysmic variable of the VY
Raymundo Baptista, Albert Bruch, Raimundo Lopes de Oliveira, Cláudia V. Rodrigues, Alexandre S. Oliveira, Isabel J. Lima   +5 more
doaj   +1 more source

The Close Binary Fraction of Dwarf M Stars [PDF]

, 2012
We describe a search for close spectroscopic dwarf M star binaries using data from the Sloan Digital Sky Survey to address the question of the rate of occurrence of multiplicity in M dwarfs.
Blake, Cullen H., Clark, Benjamin M., Knapp, Gillian R.   +2 more
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

CN Trianguli: A W-type Contact Binary Exhibiting A-type Light Curve via Starspot-induced Dimming

The Astrophysical Journal
We present comprehensive photometric observations and analysis of the totally eclipsing binary CN Tri. The photometric solutions suggest it as an extremely low mass ratio contact binary system with q ∼ 0.08.
Zhi-Hua Wang, Qing Dong, Di-Fu Guo, Si-Yu Xiao   +3 more
doaj   +1 more source

A lack of close binaries among hot horizontal branch stars in globular clusters. II. NGC\,2808

, 2011
Models based on their binary origin have been very successful in reproducing the properties of field subdwarf-B stars, but the observations of their analogues in globular clusters has posed new problems, while the discovery of multiple populations ...
Allard, Aznar Cuadrado, Bedin, Bedin, Behr, Brault, Buson, C. Moni Bidin, Caloi, Carretta, Cassisi, Catelan, Dalessandro, De Angeli, Decressin, Denissenkov, Dotter, D’Antona, D’Antona, D’Orazi, Faulkner, Ferguson, Fraix-Burnet, Fusi Pecci, G. Piotto, Greenstein, Greggio, Grundahl, Han, Han, Han, Han, Harris, Heber, Heber, Horne, Hoyle, Lee, Lisker, Maeder, Marsh, Maxted, Mengel, Miocchi, Moehler, Momany, Momany, Moni Bidin, Moni Bidin, Moni Bidin, Morales-Rueda, Morales-Rueda, Moran, Morse, Munari, Napiwotzki, Peterson, Piotto, Piotto, Piotto, Recio-Blanco, Recio-Blanco, Reed, Renzini, Rich, S. Villanova, Saffer, Sandage, Silvotti, Soker, Sosin, Suda, Sweigart, Sweigart, Tonry, Ulla, van den Bergh, von Rudloff, Williams, Y. Momany, Zorotovic   +80 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

paired: A Statistical Framework for Detecting Stellar Binarity with Gaia RVs. I. Sensitivity to Unresolved Binaries

The Astrophysical Journal
Data Release 3 (DR3) from the Gaia Mission includes radial velocity measurements of over 33 million targets. Among many scientific applications, the overlap of this stellar sample with targeted exoplanet transit survey stars presents an opportunity to ...
Quadry Chance, Daniel Foreman-Mackey, Sarah Ballard, Andrew R. Casey, Trevor J. David, Adrian M. Price-Whelan   +5 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source