Results 91 to 100 of about 3,567,567 (271)

Powroty do close reading we współczesnych lekturach literatury XX wieku

open access: yesEr(r)go, 2017
Tomasz Cieślak-Sokołowski Katedra Krytyki Współczesnej Wydział Polonistyki Uniwersytet Jagielloński The Return of Close Reading in Contemporary Interpretations of 20th Century Literatures Abstract  The present article offers an insight into ...
Tomasz Cieślak-Sokołowski
doaj  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Jemné barvy mapy Poetika setkání s druhým u Elizabeth Bishopové // Delicate colors of the map: the poetics of meeting the other in Elizabeth Bishop [PDF]

open access: yesSvět Literatury, 2015
The article offers a detailed analysis of the poem “The Map” by Elizabeth Bishop. As the opening text of Bishop’s first collection and also of all the editions of her collected poems, the poem can be read as a statement of the poet’s creative ...
Mariana Machová
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Anchored to the text, owned by the student: a policy & practice review for generative AI in literature education

open access: yesFrontiers in Education
The rapid uptake of generative AI in schools collides with a changing ecology of reading characterized by multimodality, fragmented attention, and increased reliance on short-form content. Literature education therefore faces a dual challenge: sustaining
Milan Mašát   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

The celestial ferry: Elena Shvarts’s ekphrasis as the sum of readerly experience

open access: yesСемиотические исследования
The article analyzes Elena Shvarts's late poem "Chinese Toy", where the poet describes the Kunstkamera exhibit in an unusual way, turning the mechanical principles of the ship motion and Chinese mythological imagery into a tool for blurring the ...
Alexander V. Markov, Oksana A. Bratina
doaj   +1 more source

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