Results 71 to 80 of about 3,567,567 (271)

Stepping out of Divinity: Tom King's “All-too-human” Batman

open access: yesГалактика медиа: журнал медиа исследований, 2020
This paper focuses on American superhero comics – i.e. superadventures and their likeness to mythology. Our goal is to understand how subtle changes in the characterization of a superhero may make them more congruent with the present day morality and ...
Taynah Ibanez Barbosa   +1 more
doaj   +1 more source

How Close Reading Influences Reading Comprehension [PDF]

open access: yes, 2017
: Assessments at the international, national, state, and local levels demonstrate that students’ reading scores in Arizona lack growth. Current trends in education encourage teachers to engage in close reading as a strategy to help improve reading ...

core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Travelling TexTs alla Nordic Digital Humanities Conference: Riflessioni sulla situazione di Digital Humanities nell’ottica della storia letteraria finlandese

open access: yesLea, 2016
In my contribution, I intend to offer a report on the first conference of Nordic Digital Humanities held in Oslo on March 15-17 2016. I begin with a brief note on the present situation of the discipline, and, following the arguments brought up during the
Viola Parente-Čapková
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

O Literário Será Sempre Moderno? O Novo Nostálgico da Literatura Eletrónica

open access: yesMatLit, 2015
Review of Jessica Pressman, Digital Modernism: Making it New in New Media, Oxford, Oxford University Press, 2014, 240 pp. [1ª ed.].
Bettencourt, Sandra
doaj   +1 more source

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