Results 51 to 60 of about 11,686 (264)

Sustainable humanitarian operations: closed-loop supply chain [PDF]

open access: yesInternational Journal of Services and Operations Management, 2016
This paper explores the closed loop supply chain (CLSC) topic by providing a model and evaluating regular humanitarian logistics (R-HL) where the main objective of the operation moves from the reduction of population needs to a minimisation of the overall impact of the disaster and operations.
BATTINI, DARIA   +3 more
openaire   +2 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Designing a Green Closed-loop Supply Chain Simulation Model and Product Pricing in The Presence of a Competitor [PDF]

open access: yesMuṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2019
The increasing concern about the deteriorating effects of supply chains related activities on the environment has led to the growing attention to develop green closed-loop supply chains in order to minimize greenhouse gases emission.
Samira Parsaiyan   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Special Section: Closed-Loop Supply Chains: Practice and Potential: The Challenge of Closed-Loop Supply Chains.

open access: yesInterfaces, 2003
Closed-loop supply chains differ significantly from forward supply chains in many aspects. These differences are not well understood in many contexts, and the situation is complicated by many types of product returns. Progress is slow since closed-loop supply chains are rarely considered as value-creating systems, and much of the focus is on the ...
V. Daniel R. Guide Jr.   +2 more
openaire   +2 more sources

Closed-loop supply chain network equilibrium strategy model with environmental protection objectives

open access: yesChinese Journal of Population, Resources and Environment, 2020
With the increasing popularity of ecological civilization and sustainable development, enterprises should consider environmental protection measures in their operations in addition to pursue their economic interests.
Yang Liu, Guitao Zhang
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Proposing Model for Master Planning of Sustainable Supply Chain with Considering Integration of Physical and Financial Flow [PDF]

open access: yesچشم‌انداز مدیریت صنعتی, 2018
Balance growth in economic, social and environmental dimensions, and integrity of financial and physical flow of supply chain can ensure long-term success of any supply chain.
Amir Salar Mohammadi   +2 more
doaj  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

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