Results 101 to 110 of about 157,330 (294)
An Obstruction-Check Approach to Mining Closed Sequential Patterns in Data Streams
, 2010 Online mining sequential patterns over data streams is an important problem in data mining. There are many applications of using sequential patterns in data streams, such as market analysis, network security, sensor networks and web track- ing.
Chin, Tsz-lin
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Maximal sequential patterns mining with timing constraints
, 2010 碩士循序樣式探勘的目的是從資料庫中，尋找頻繁出現且有順序的樣式，通常這些樣式會再被轉換成先前所不知道的、有用的與有價值的資訊。由於資料庫中通常存在大量且長時間的資料，因此循序樣式探勘往往需要花上大量時間。但是一般的頻繁循序樣式探勘演算法無法針對要尋找之頻繁循序樣式的時間條件加以限制，使得探勘得到的頻繁循序樣式太多且不易應用。探勘最長頻繁循序樣式雖可得到意義相同且較精簡的樣式集合，但針對長度為k之最長頻繁循序樣式探勘，不論是以PrefixSpan或是Apriori為基礎的演算法皆必須經過k個回合的探勘 ...
林師晟; Lin, Shi-cheng
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Mining Maximal Sequential Patterns in Protein Databases
, 2007 蛋白質序列中的序列樣式，和蛋白質所執行的功能有著密不可分的關係。因此，如何從蛋白質序列資料庫中，透過系統化的方法，探勘出重要的序列樣式，已成為一個相當重要的研究課題。 針對此一課題，本論文提出了一個以字尾樹(suffix tree)為基礎的演算法。演算法中的所有過程，包括探勘序列樣式中的封閉性高頻子字串(closed frequent substring)，將封閉性子字串組成最大高頻序列樣式(maximal frequent sequential pattern)，以及調整序列樣式中子字串間的間隔 ...
凌宇, Ling, Yu
core
Using extended random set to find specific patterns
, 2014 With the overwhelming increase in the amount of data on the web and data bases, many text mining techniques have been proposed for mining useful patterns in text documents.
Albathan, Mubarak +5 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
A novel algorithm for mining closed temporal patterns from interval-based data
, 2016 補正完
Hui, Lin +2 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source