Results 31 to 40 of about 4,031,702 (245)
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
An investigation of Hebbian phase sequences as assembly graphs
Hebb proposed that synapses between neurons that fire synchronously are strengthened, forming cell assemblies and phase sequences. The former, on a shorter scale, are ensembles of synchronized cells that function transiently as a closed processing system;
Daniel Gomes Almeida Filho +6 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Incremental Mining of Closed Sequential Patterns in Multiple Data Streams
Sequential pattern mining searches for the relative sequence of events, allowing users to make predictions on discovered sequential patterns. Due to drastically advanced information technology over recent years, data have rapidly changed, growth in data ...
Yang, Shih-yang; Chao, Ching-ming; Chen, Po-zung; Sun, Chu-hao
core +1 more source
Discover Sequential Patterns in Incremental Database
The task of sequential pattern mining is to discover the complete set of sequential patterns in a given sequence database with minimum support threshold.
Lin, Nancy P.; Hao, Wei Hua; Chen, Hung Jen; Chueh, Hao En; Chang, Chung I
core +1 more source
Graph-based discovery of ontology change patterns [PDF]
Ontologies can support a variety of purposes, ranging from capturing conceptual knowledge to the organisation of digital content and information. However, information systems are always subject to change and ontology change management can pose challenges.
Abgaz, Yalemisew +2 more
core +2 more sources
A hybrid method for winter road surface temperature prediction using improved LSTMs and stacking-based ensemble learning [PDF]
Accurate prediction of road surface temperature (RST) is essential for proactive winter road maintenance and traffic safety management. However, existing approaches – ranging from physics-based models to data-driven methods – either require detailed ...
W. Li +14 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

