Results 41 to 50 of about 4,031,702 (245)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Streamflow prediction using an incremental attention network with LSTM and Chaos optimization techniques

Ain Shams Engineering Journal
Accurate streamflow prediction is vital for effective water resource management, flood control, and hydrological modeling. This study presents a novel hybrid framework that integrates an Incremental Attention Network (IAN) with Long Short-Term Memory ...
Sina Apak, Huseyin Cagan Kilinc, Adem Yurtsever   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design of an Improved Model for Anomaly Detection in CCTV Systems Using Multimodal Fusion and Attention-Based Networks

IEEE Access
Traditional approaches for video analysis often misdefine anomalies; they usually rely on single-modality input and have inadequate management of complex temporal patterns.
V. Srilakshmi, Sai Babu Veesam, Mallu Shiva Rama Krishna, Ravi Kumar Munaganuri, Dulam Devee Sivaprasad   +4 more
doaj   +1 more source

Collaborative Governance, Knowledge Interfaces, and Flow Closed-Loop: A Mechanism Study on Rural Reading Spaces as Agricultural Knowledge Diffusion Nodes [PDF]

Nongye tushu qingbao xuebao
[Purpose/Significance] The effective flow of agricultural knowledge from innovation sources to fields is a core component of agricultural modernization. However, a persistent "structural knowledge gap" exists between macro-level knowledge supply and the ...
WANG Jian
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Enhancing Vocabulary Acquisition and Language Learning Through Corpus Linguistic Approaches: The Role of Onomastics in Teaching Batik Madura’s Cultural Identity

Journal of Teaching and Learning
Research on corpus linguistics in language learning has primarily emphasized lexical patterns, collocations, and discourse structures, yet their application to onomastics remains underexplored.
Suhartatik, Wahyudi Siswanto, Roekhan
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

RT-Sort: An action potential propagation-based algorithm for real time spike detection and sorting with millisecond latencies.

PLoS ONE
With the use of high-density multi-electrode recording devices, electrophysiological signals resulting from action potentials of individual neurons can now be reliably detected on multiple adjacent recording electrodes.
Tjitse van der Molen, Max Lim, Julian Bartram, Zhuowei Cheng, Ash Robbins, David F Parks, Linda R Petzold, Andreas Hierlemann, David Haussler, Paul K Hansma, Kenneth R Tovar, Kenneth S Kosik   +11 more
doaj   +1 more source