Results 121 to 130 of about 7,966 (294)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

La estructura del reportaje en radio

open access: yesÁrea Abierta, 2007
The feature is a model of representation of the reality that from the monologue tries to narrate and describe facts and actions of interest for the listener, providing a wide context of interpretation in the contents and a use of sources diverse and ...
Susana Herrera Damas
doaj  

Closeness and Residual Closeness of Harary Graphs

open access: yesFundamenta Informaticae
Analysis of a network in terms of vulnerability is one of the most significant problems. Graph theory serves as a valuable tool for solving complex network problems, and there exist numerous graph-theoretic parameters to analyze the system's stability.
Hande Tuncel Golpek, Aysun Aytaç
openaire   +3 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Medical image segmentation using openings and closings with reconstruction criteria

open access: yes, 2003
In this paper, we use a type of morphological filters, the openings and closings with reconstruction criteria, for image segmentation purposes. Those filters are a class of extended levelings, and they present interesting features for image processing ...
Maojo Garcia, Victor Manuel   +3 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Municipal Hospital Closings Under Title VI: A Requirement of Reasonable Justifications [PDF]

open access: yes, 1981
Municipal hospital closings in recent years are a by-product of two phenomena: 1) the dramatic increase in health care costs and, 2) the fiscal crisis facing many cities. The impact of this reduction in municipal services is felt most acutely by indigent
Cimkowski, Carol A.
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

“Je serais très merciable”: Formulaic vs. Creatively Produced Speech in Learners’ Request-Closings

open access: yesCanadian Journal of Applied Linguistics, 2005
This paper reports the findings of a study on intermediate classroom learners’ ability to perform appropriate formulaic sequences (FSs) for closing high-imposition requests.
Muriel Warga
doaj  

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