Results 91 to 100 of about 38,675 (255)

In silico exploration of Red Sea Bacillus genomes for natural product biosynthetic gene clusters [PDF]

open access: yes, 2018
Background: The increasing spectrum of multidrug-resistant bacteria is a major global public health concern, necessitating discovery of novel antimicrobial agents. Here, members of the genus Bacillus are investigated as a potentially attractive source of
A Alvarez-Ordonez   +81 more
core   +3 more sources

Preoperative Cytopenia in Patients Affected by High‐Risk Neuroblastoma: Just a Matter of Platelets?

open access: yesPediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background and Aims In patients affected by high‐risk neuroblastoma (HR‐NB), complete macroscopic resection (CMR) is associated with better outcomes. These patients are often cytopenic due to intensive induction regimens. The aim of the present study is to assess the impact of preoperative cytopenia on surgical outcome in patients with HR‐NB ...
Giorgio Persano   +13 more
wiley   +1 more source

Epidemiology of Clostridioides difficile Infections in Germany, 2010–2019: A Review from Four Public Databases

open access: yesInfectious Diseases and Therapy, 2023
Introduction Clostridioides difficile infection (CDI) is a recognized global threat especially for vulnerable populations. It is of particular concern to healthcare providers as it is found in both hospital and community settings, with severe courses ...
Gordon Brestrich   +15 more
doaj   +1 more source

Development of Peptide Glucosyltransferase Inhibitors With Comprehensive Coverage Across Clostridioides difficile Toxin B Sub‐Types

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 2, Page 310-323, February 2026.
ABSTRACT Clostridioides difficile infection presents an escalating clinical challenge due to the proliferation of hypervirulent and antibiotic‐resistant strains. The primary symptoms of disease, namely colitis and diarrhea, are induced by the release of two toxins: TcdA and TcdB.
Carly M. Catella   +10 more
wiley   +1 more source

Case report of two patients with recurrent watery stools following prophylactic ileostomy reversal after rectal cancer surgery

open access: yes结直肠肛门外科
The causes of diarrhea after enterostomy reversal may be related to surgical treatment, and its severity varies. Clinical interventions are often based on the patient’s symptomatic presentation.
Shen Shuai, Gao Hui
doaj   +1 more source

Presence of Clostridium difficile in poultry and poultry meat in Egypt [PDF]

open access: yes, 2018
C. difficile has been recognized as a potential zoonotic agent encouraging investigations of C. difficile prevalence and ribotypes in animals. Here we report the prevalence and diversity of Egyptian C. difficile in I) samples from healthy poultry (n = 50)
Abdel-Glil, Mostafa Y.   +6 more
core   +3 more sources

Hospital Infection Control: Clostridioides difficile

open access: yesClinics in Colon and Rectal Surgery, 2020
Abstract Clostridioides difficile remains a leading cause of healthcare-associated infection. Efforts at C. difficile prevention have been hampered by an increasingly complex understanding of transmission patterns and a high degree of heterogeneity among existing studies. Effective prevention of C.
Turner, Nicholas A, Anderson, Deverick J
openaire   +3 more sources

Knowledge, Attitude, and the Practice in Nosocomial Infection Control Among Afghan Healthcare Workers in Herat Afghanistan: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Hospital‐acquired infections (HIAs) remain a major threat to patient and healthcare worker (HCW) safety globally, with higher burden in low‐resource settings. Despite moderate knowledge among HCWs in many low‐income contexts, actual adherence to infection prevention practices is often poor.
Mohammad Masudi   +6 more
wiley   +1 more source

Genomic characterization of nine Clostridioides difficile strains isolated from Korean patients with Clostridioides difficile infection

open access: yesGut Pathogens, 2021
Background Clostridioides difficile infection (CDI) is an infectious nosocomial disease caused by Clostridioides difficile, an opportunistic pathogen that occurs in the intestine after extensive antibiotic regimens. Results Nine C.
Seung Woo Ahn   +7 more
doaj   +1 more source

Activity Profiling of Nitro‐Substituted Di(Hetero)Aryl 1,3,4‐ and 1,2,4‐Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential

open access: yesArchiv der Pharmazie, Volume 359, Issue 1, January 2026.
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová   +9 more
wiley   +1 more source

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