Strategies to prevent Clostridioides difficile infections in acute-care hospitals: 2022 Update
Larry K. Kociolek MD, MSCI1 , Dale N. Gerding MD2 , Ruth Carrico PhD, DNP, APRN, CIC3 , Philip Carling MD4 , Curtis J. Donskey MD5 , Ghinwa Dumyati MD6 , David T. Kuhar MD7, Vivian G. Loo MD, MSc8, Lisa L.
L. Kociolek+13 more
semanticscholar +1 more source
The repertoire of ABC proteins in Clostridioides difficile
ATP-binding cassette (ABC) transporters belong to one of the largest membrane protein superfamilies, which function in translocating substrates across biological membranes using energy from ATP hydrolysis. Currently, the classification of ABC transporters in Clostridioides difficile is not complete.
Matthew Phanchana+6 more
openaire +4 more sources
COVID-19 and Clostridioides difficile Coinfection Analysis in the Intensive Care Unit
Since the emergence of SARS-CoV-2 in late 2019, the global mortality attributable to COVID-19 has reached 6,972,152 deaths according to the World Health Organization (WHO).
M. Stoian+9 more
semanticscholar +1 more source
Clostridioides difficile Flagella
Clostridioides difficile is an important pathogen for humans with a lead in nosocomial infection, but it is also more and more common in communities. Our knowledge of the pathology has historically been focused on the toxins produced by the bacteria that remain its major virulence factors.
Jean-Christophe Marvaud+3 more
openaire +2 more sources
Clostridioides difficile: A diagnostic intervention
Background:Clostridioides difficile infection (CDI) is a leading cause of healthcare-associated infection and is associated with increased morbidity and mortality. Multiple strategies have been implemented to optimize the diagnostic accuracy of CDI testing algorithms. However, overdiagnosis of C. difficile colonization remains a challenge especially in
Majd Alsoubani+3 more
openaire +2 more sources
Antibiotic-associated colitis is often caused by infection with the bacterium Clostridioides difficileC ...
Jhansi L. Leslie+10 more
doaj +1 more source
Epidemiologia da Infeção por Clostridioides Difficile em Portugal: um Estudo Retrospetivo, Observacional em Doentes Hospitalizados [PDF]
Introduction: Clostridioides difficile is the main cause of healthcare-associated diarrhea in Europe and North America. The aim of this study was to characterize the epidemiology and clinical burden of Clostridioides difficile infection among ...
Cunha, F+14 more
core +2 more sources
Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia+12 more
wiley +1 more source
Evaluating Healthcare-Associated Infections in Public Hospitals: A Cross-Sectional Study
Background: Hospital-acquired infections (HAIs) pose a significant danger to global public health, mainly because their numbers are growing exponentially each year.
Daniela Iancu+3 more
doaj +1 more source
Clostridioides difficile infection in a long-term convalescence hospital: A real tale of pitfalls and outdated therapy [PDF]
Objective. The aim of the study was to know the char-acteristics and risk factors of Clostridioides difficile infection (CDI) in a long-term hospital is key to improve its manage-ment. Material and methods.
Esteban-Rihuete, M.+5 more
core +1 more source