Results 111 to 120 of about 40,986 (311)

Update on commonly used molecular typing methods for Clostridioides Difficile [PDF]

open access: yes, 2023
This review aims to provide a comprehensive overview of the significant Clostridioides difficile molecular typing techniques currently employed in research and medical communities.
Abad-Fau, Ana   +4 more
core   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

open access: yesExploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang   +4 more
wiley   +1 more source

Recommendations for the management of Clostridioides difficile infection in adults and comparison with updated ACG, ESCMID and IDSA/SHEA guidelines

open access: yesFamily Medicine & Primary Care Review
Clostridioides difficile infection is the most common cause of antibiotic-associated diarrhea. IDSA/SHEA, ESCMID and ACG updated the clinical practice guidelines for CDI in 2021. This paper is an attempt to summarize these guidelines.
Mateusz Piotr Baran   +4 more
doaj   +1 more source

Cytotoxic synergism of Clostridioides difficile toxin B with proinflammatory cytokines in subjects with inflammatory bowel diseases [PDF]

open access: yes, 2023
Clostridioides difficile (C. difficile) is progressively colonizing humans and animals living with humans. During this process, hypervirulent strains and mutated toxin A and B of C. difficile (TcdA and TcdB) are originating and developing.
Bassotti, Gabrio   +4 more
core   +1 more source

Gut microbiota and tuberculosis

open access: yesiMeta, EarlyView.
This review explores the intricate relationship between gut microbiota (GM) and tuberculosis (TB). The figure illustrates the bidirectional effects between GM dynamics and TB progression, as well as the interactions between the GM and antituberculosis drugs.
Yanhua Liu   +39 more
wiley   +1 more source

Clostridioides difficile and Gut Microbiota: From Colonization to Infection and Treatment

open access: yesPathogens
Clostridioides difficile is the main causative agent of antibiotic-associated diarrhea (AAD) in hospitals in the developed world. Both infected patients and asymptomatic colonized individuals represent important transmission sources of C. difficile.
P. Spigaglia
semanticscholar   +1 more source

Fidaxomicin to prevent recurrent Clostridioides difficile: what will it cost in the USA and Canada?

open access: yesJAC-Antimicrobial Resistance, 2023
Importance Recent changes in guidelines for managing Clostridioides difficile infections (CDI) have placed fidaxomicin as a first-line treatment. Objective To estimate the net cost of first-line fidaxomicin compared to vancomycin in the American and ...
Devangi Patel   +7 more
semanticscholar   +1 more source

An incidental finding of mesenteric hematoma in a patient with a new diagnosis of inflammatory bowel disease

open access: yesJPGN Reports, EarlyView.
Abstract Mesenteric hematomas (MHs) are relatively rare and are characterized by localized bleeding in the mesenteric vascular tree presenting with abdominal pain, vomiting, abdominal distension, masses, and hypotension. We report a case of a MH which was incidentally found in a 10‐year‐old patient with a new diagnosis of ulcerative colitis (UC).
Breanna Brown   +2 more
wiley   +1 more source

Incidence and Outcomes Associated With Clostridium difficile Infections: A Systematic Review and Meta-analysis [PDF]

open access: yes, 2020
Importance: An understanding of the incidence and outcomes of Clostridium difficile infection (CDI) in the United States can inform investments in prevention and treatment interventions.
Balkenende, Erin   +15 more
core   +1 more source

Expanding Our Grasp of Two-Component Signaling in \u3ci\u3eClostridioides difficile\u3c/i\u3e [PDF]

open access: yes, 2023
The intestinal pathogen Clostridioides difficile encodes roughly 50 TCS, but very few have been characterized in terms of their activating signals or their regulatory roles. A. G. Pannullo, B. R. Zbylicki, and C. D. Ellermeier (J Bacteriol 205:e00164-23,
Alvarez, Orlando Berumen   +1 more
core   +1 more source

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