Results 131 to 140 of about 28,268 (242)

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

MedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait, Anna Cargnoni, Franco Scaldaferri, Loris Lopetuso, Antonietta Rosa Silini, Ornella Parolini   +5 more
wiley   +1 more source

Antimicrobial Resistance of Clostridioides difficile in Children from a Tertiary Pediatric Hospital in Shanghai, China

Xiaolu Li,1,* Yizhong Wang,1,2,* Rong Cao,1 Fangfei Xiao,1 Xufei Wang,1 Lin Ye,1 Yongmei Xiao,1 Dan Li,1 Ting Zhang1,2 1Department of Gastroenterology, Hepatology and Nutrition, Shanghai Children’s Hospital, School of Medicine, Shanghai Jiao Tong
Li X, Ye L, Zhang T, Li D, Xiao Y, Xiao F, Wang X, Wang Y, Cao R   +8 more
core  

Overtreatment of Clostridioides difficile Colonization for Patients Residing in Davidson County, Tennessee from 2018–2022

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Clostridioides difficile is one of the most common healthcare associated infections. Due to diagnostic uncertainty, patients are often treated for colonization instead of infection.
Natalie Stanley, Sarah Petersen, Malakai Miller, Samantha Mathieson, Simone Godwin   +4 more
doaj   +1 more source

Microbial Signals in Cancer: Dissecting Host–Microbiota–Tumor Interactions and Potential Therapeutic Strategy

MedComm, Volume 7, Issue 9, September 2026.
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu, Mengjuan Xuan, Liang Yu, Zhongyang Xie, Qingfei Chu, Shihui Wei, Tuokai Wang, Chen Xue, Lanjuan Li   +8 more
wiley   +1 more source

Multiplex PCR to Diagnose Gastrointestinal Infections: Key Limitations in Interpretation

United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
ABSTRACT Multiplex polymerase chain reaction (PCR) panels are increasingly used for the evaluation of acute diarrhea, providing rapid and sensitive detection of a broad range of enteric pathogens. However, their widespread adoption has created important interpretive challenges for clinicians.
Giannoula S. Tansarli, Ferric C. Fang
wiley   +1 more source

Risk factors for further recurrences of Clostridioides difficile infection at the first and second recurrence: a retrospective cohort

BMC Infectious Diseases
Background Recurrent Clostridioides difficile infection is most effectively treated with faecal microbiota transplantation. Swedish and European guidelines suggest faecal microbiota transplantation after a first or second recurrence, respectively.
Måns Stefansson, Oscar Bladh, Piotr Nowak, Lars Rombo, Magnus Hedenstierna, Johan Ursing   +5 more
doaj   +1 more source

Patterns of Surgical Prophylaxis Prescribing for Dentoalveolar Procedures in Australian Hospitals: 2016–2022

Australian Dental Journal, Volume 71, Issue 3, Page 231-241, September 2026.
ABSTRACT Background Antimicrobials are an adjunctive therapy in clinical dentistry. In dentoalveolar surgery, antimicrobials are not routinely required for surgical prophylaxis. This retrospective analysis of the Australian Surgical National Antimicrobial Prescribing Survey (Surgical NAPS) dataset aimed to evaluate the guideline compliance and ...
Jane Chen, Marietta Taylor, Rodney James, Karin Thursky, Michael McCullough, Leanne Teoh, Courtney Ierano   +6 more
wiley   +1 more source

The current riboswitch landscape in Clostridioides difficile

International audienceRiboswitches are 5′ RNA regulatory elements that are capable of binding to various ligands, such as small metabolites, ions and tRNAs, leading to conformational changes and affecting gene transcription or translation.
Soutourina, Olga, Badilla Lobo, Adriana, Peltier, Johann   +2 more
core   +1 more source

Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 6, Page 729-747, September 2026.
The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins, Srinivas Kamath, Rachel H. Davis, Samuel P. Costello, Robert V. Bryant, Alice S. Day, Paul Joyce   +6 more
wiley   +1 more source

Postoperative Care and Management in Pediatric Hematology‐Oncology Patients

European Journal of Haematology, Volume 117, Issue 3, Page 673-681, September 2026.
ABSTRACT Pediatric patients with hematologic and oncologic diseases often undergo surgical procedures as part of diagnosis and therapy. These include central venous catheter placements, tumor resections, lymph node and bone marrow biopsies, among others.
Shachi Srivatsa, Sara A. Mansfield
wiley   +1 more source