Management of Clostridioides difficile infection: an Italian Delphi consensus [PDF]
Background: Clostridioides difficile infection (CDI), a leading cause of nosocomial deaths, is a microbiota-mediated disease. As such, the use of broader spectrum antibiotics, such as vancomycin and metronidazole, can prime the gastrointestinal tract to ...
Armuzzi, Alessandro +12 more
core +2 more sources
Effective fecal microbiota transplantation for recurrent Clostridioides difficile infection in humans is associated with increased signalling in the bile acid-farnesoid X receptor-fibroblast growth factor pathway [PDF]
Tanya Monaghan +7 more
openalex +1 more source
Real-world Effectiveness of Fecal Microbiota Transplantation for First or Second Clostridioides difficile Infection [PDF]
Background & Aims: Clostridioides difficile infection (CDI) is associated with high mortality. Fecal microbiota transplantation (FMT) is an established treatment for recurrent CDI, but its use for first or second CDI remains experimental. We aimed to
Baumwall, Simon Mark Dahl +20 more
core +1 more source
Bacteriophages Contribute to Shaping Clostridioides (Clostridium) difficile Species [PDF]
Louis‐Charles Fortier
openalex +1 more source
Environmental transmission of Clostridioides difficile ribotype 027 at a long-term care facility; an outbreak investigation guided by whole genome sequencing [PDF]
Bradley T. Endres +15 more
openalex +1 more source
Clostridioides difficile (CD) infections are defined by toxins A (TcdA) and B (TcdB) along with the binary toxin (CDT). The emergence of the ‘hypervirulent’ (Hv) strain PR 027, along with PR 176 and 181, two decades ago, reshaped CD infection ...
Alexandre Godmer +10 more
doaj +1 more source
Difference in Mono-O-Glucosylation of Ras Subtype GTPases Between Toxin A and Toxin B From Clostridioides difficile Strain 10463 and Lethal Toxin From Clostridium sordellii Strain 6018 [PDF]
Harald Genth +7 more
openalex +1 more source
Treatment of Clostridioides Difficile with Fecal Microbiota Transplantation [PDF]
Research was performed to discuss the epidemiology and current guidelines of Clostridioides difficile infection (CDI), recurrent C. difficile infection (rCDI), the different modalities of fecal microbiota transplantation (FMT), the donor screening ...
Green, Brenton
core +2 more sources
Cost Analysis of Computerized Clinical Decision Support and Trainee Financial Incentive for Clostridioides difficile Testing [PDF]
Gregory R. Madden +5 more
openalex +1 more source
Comparison of fidaxomicin, metronidazole and vancomycin for initial episode and recurrence of Clostridioides difficile infection - An observational cohort study [PDF]
Objectives The main aim of this study was to compare the clinical outcomes of patients attended in our area with Clostridioides difficile infection (CDI) (sustained cure, recurrence or death) in relation to treatment to normal or hypervirulent C ...
Cuadros González, Juan +4 more
core +1 more source

