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Clostridioides difficile Biofilm

Clostridioides difficile infection (CDI), previously Clostridium difficile infection, is a symptomatic infection of the large intestine caused by the spore-forming anaerobic, gram-positive bacterium Clostridioides difficile. CDI is an important healthcare-associated disease worldwide, characterized by high levels of recurrence, morbidity, and mortality.
Claudia, Vuotto   +3 more
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Clostridioides difficile: diagnosis and treatments

BMJ, 2019
AbstractClostridioides difficile(formerlyClostridium) is a major cause of healthcare associated diarrhea, and is increasingly present in the community. Historically,C difficileinfection was considered easy to diagnose and treat. Over the past two decades, however, diagnostic techniques have changed in line with a greater understanding of the ...
Frédéric Barbut   +2 more
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Clostridioides difficile and Norovirus

2019
Clostridioides difficile and norovirus are common causes of healthcare-associated gastroenteritis and both organisms cause outbreaks in pediatric healthcare settings. The spores are resistant to routine environmental cleaning with detergents and can survive in the environment for months. C.
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Clostridioides difficile infection diagnosis

Annales de Biologie Clinique
Clostridioides difficile is a Gram-positive, spore-forming anaerobic enteropathogen responsible for a wide spectrum of clinical diseases ranging from mild diarrhoea to pseudomembranous colitis. It is the first cause of healthcare-associated diarrhoeas, but community-associated Clostridioides difficile infections (CDI) are increasingly reported in ...
Jeanne, Couturier   +3 more
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Microscopy methods for Clostridioides difficile

Anaerobe
Microscopic technologies including light and fluorescent, transmission electron microscopy (TEM), scanning electron microscopy (SEM), and cryo-electron microscopy have been widely utilized to visualize Clostridioides difficile at the molecular, cellular, community, and structural biology level. This comprehensive review summarizes the microscopy tools (
Chenlin Hu, Kevin W. Garey
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Foodborne transmission of Clostridioides difficile

Current Opinion in Gastroenterology, 2020
The epidemiology of Clostridioides difficile infection (CDI) is changing, with increasing rates of community-acquired infections. In light of recent advances in understanding C. difficile transmission networks with whole-genome sequencing, new routes of spread outside the hospital need to be considered.
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Antibiotic Resistances of Clostridioides difficile

The rapid evolution of antibiotic resistance in Clostridioides difficile and the consequent effects on prevention and treatment of C. difficile infections (CDIs) are a matter of concern for public health. Antibiotic resistance plays an important role in driving C. difficile epidemiology.
Patrizia, Spigaglia   +2 more
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Comparative Genomics of Clostridioides difficile

Clostridioides difficile, a Gram-positive spore-forming anaerobic bacterium, has rapidly emerged as the leading cause of nosocomial diarrhoea in hospitals. The availability of large numbers of genome sequences, mainly due to the use of next-generation sequencing methods, has undoubtedly shown their immense advantages in the determination of C ...
Sandra, Janezic   +2 more
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Clostridioides-difficile-Infektion

2021
Norbert Lügering, Andreas Stallmach
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CLOSTRIDIOIDES DIFFICILE IN HOSPITAL SETTINGS

The past decades have witnessed a significant global increase in the incidence and severity of Clostridioides difficile (C. diff) infection. This pathogen has long been among the most burdensome hospital infections, but it has now become a leading factor contributing to morbidity and mortality from infectious diseases in developed countries.
Ristić R.   +3 more
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