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CLOSTRIDIUM | Detection of Neurotoxins of Clostridium botulinum

2014
Botulism is caused by an exotoxin produced by the sporeforming bacterium Clostridium botulinum. Of the seven different toxin types, A, B, and E are the types commonly implicated in foodborne outbreaks of botulism. Clostridium botulinum toxins are extremely potent neurotoxins and generally occur at low concentrations in implicated foods.
Notermans, S.H.W.   +2 more
openaire   +2 more sources

Pathogenicity of Clostridium Botulinum

Journal of Infectious Diseases, 1925
The pathogenicity of Clostridium botulinum has been the subject of much laboratory work with variable results. Botulism in man is unquestionably a true intoxication caused by the soluble toxin elaborated by CI. botulinum under saprophytic conditions. There is a possibility, however, that the organism itself may multiply and produce this toxin within ...
William A. Starin, Gail M. Dack
openaire   +2 more sources

Clostridium botulinum Subtype Ba Clostridium botulinum Subtyp Ba

Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale. A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie, 1984
Summary Strain 657 has been described as a toxin variant of Clostridium botulinum type B. Neutralization tests performed with types A and B botulinal antitoxins of known potency and avidity at 20, 25, 50, 100, 200, 2,000 and 20,000 mouse LD 50 levels of testing, have shown that 657 toxin is a mixture of B (approximately 95 % of the complex) and A ...
openaire   +2 more sources

Immunofluorescent Identification of Clostridium botulinum

Nature, 1964
THE detection of Clostridium botulinum usually involves culturing the suspect sample, and then testing the culture for the presence of botulinum toxin. The toxin is identified by mouse protection tests using specific botulinum antitoxins1, a procedure complicated by the known existence of six different types of Cl.
D. L. Georgala, Margery Boothroyd
openaire   +3 more sources

Association of toxin-producing Clostridium botulinum with the macroalga Cladophora in the Great Lakes.

Environmental Science and Technology, 2013
Avian botulism, a paralytic disease of birds, often occurs on a yearly cycle and is increasingly becoming more common in the Great Lakes. Outbreaks are caused by bird ingestion of neurotoxins produced by Clostridium botulinum, a spore-forming, gram ...
C. Chun   +8 more
semanticscholar   +1 more source

Clostridium botulinum

Foodborne Infections and Intoxications, 2021
Jeremy Sobel, Carolina Lúquez
semanticscholar   +1 more source

CLOSTRIDIUM BOTULINUM TYPE B TOXOIDS

Canadian Journal of Research, 1947
Fluid and alum-precipitated C. botulinum Type B toxoids were prepared by methods very similar to those used in the production of Type A toxoid, as described in a preceding paper. These Type B toxoids had little protective effect in mice but induced a moderately high degree of immunity in guinea-pigs as shown by their resistance to multiple lethal ...
Christine E. Rice   +3 more
openaire   +5 more sources

Clostridium botulinum, Clostridium perfringens, Clostridium difficile

2018
Members of the genus Clostridium cause a variety of diseases in humans and animals, sometimes with fatal consequences. These organisms are anaerobic spore-forming rod-shaped bacteria and mostly associated with soil and sediments. Three species, Clostridium botulinum, C. perfringens and C. difficile, have a significant importance because these pathogens
openaire   +2 more sources

CLOSTRIDIUM BOTULINUM AND NEAR-MISS SIDS

The Lancet, 1985
SCOPUS: le.j ; info:eu-repo/semantics ...
Kahn, André   +2 more
openaire   +3 more sources

Binding of Clostridium botulinum Neurotoxin to Gangliosides1

The Journal of Biochemistry, 1986
The binding characteristics of Clostridium botulinum neurotoxins of types B, C1, and F to gangliosides was studied by thin layer chromatography plate and microtiter plate methods at low (10 mM NaCl in 10 mM Tris-HCl buffer, pH 7.2) or high (150 mM NaCl in 10 mM Tris-HCl buffer, pH 7.2) ionic strengths and at 0 or 37 degrees C. The three types of toxins
Ochanda James O.   +4 more
openaire   +3 more sources

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