Results 91 to 100 of about 113,640 (277)

Glycoproteomics and Its Role in Understanding Bacterial O‐Linked Glycosylation

PROTEOMICS, EarlyView.
ABSTRACT Protein glycosylation is now recognized as a ubiquitous process observed in all domains of life. Within bacterial species, carbohydrates can be attached to multiple residues with glycosylation of serine, threonine, or tyrosine residues via their hydroxyl side chains referred to as O‐linked glycosylation.
Kristian I. Karlic, Hamza Tahir, Nichollas E. Scott   +2 more
wiley   +1 more source

Diarrhoea caused by Clostridium difficile in patients with postoperative subhepatic abscess [PDF]

, 2008
Background. Toxigenic strains of Clostridium difficile in the majority of cases cause disease of the intestinal tract of hospitalized patients. For a long time, Clostridium difficile was considered to produce both types of toxins (A+/B+ strain), however,
Kocić Branislava, Stojanović Predrag
core   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Health outcomes of statin users compared to non-users with Clostridium difficile infection [PDF]

, 2017
Background: Clostridium difficile infection (CDI) is the most common cause of nosocomial diarrhea, and the primary cause of healthcare-associated infections in the United States. Statins have beneficial effects independent of their lipid-lowering effects;
Argamany, Jacqueline Rose
core   +1 more source

Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research

United European Gastroenterology Journal, EarlyView.
ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch, Celia Escudero‐Hernández   +1 more
wiley   +1 more source

Recurrent Pseudomembranous Colitis in an Ovarian Cancer Patient Undergoing Carboplatin Chemotherapy

Case Reports in Obstetrics and Gynecology, 2016
Background. Diarrhea is a common problem in ovarian cancer patients undergoing chemotherapy and Clostridium difficile infection has been identified as a cause.
Valerie A. Allen, Kelly J. Manahan, John P. Geisler   +2 more
doaj   +1 more source

Bezlotoxumab for prevention of recurrent Clostridium difficile infection in patients at increased risk for recurrence [PDF]

, 2018
Background: Bezlotoxumab is a human monoclonal antibody against Clostridium difficile toxin B indicated to prevent C. difficile infection (CDI) recurrence (rCDI) in adults at high risk for rCDI. This post hoc analysis of pooled monocolonal antibodies for
Dorr, Mary Beth, Dubberke, Erik R, Ellison, Misoo C, Eves, Karen, Gerding, Dale N, Guris, Dalya, Hanson, Mary E, Kao, Dina, Kelly, Ciaran P, Kumar, Princy N, Lee, Christine, Rahav, Galia, Yacyshyn, Bruce   +12 more
core   +2 more sources

Gut Microbial Signatures Associated With Clinical Remission in Inflammatory Bowel Disease Treated With Biologics: A Comprehensive Multi‐Cohort Analysis

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background and Aims The relationship between gut microbiota and biological treatment response in inflammatory bowel disease (IBD) remains incompletely understood. We sought to characterize microbial signatures associated with clinical remission and develop a prediction model for clinical remission. Methods We analyzed 16 S rRNA gene sequencing
Qingyang Zheng, Yun Zhong, Haifeng Lian, Jieru Zhuang, Lichun Wang, Jianyong Chen, Huaiming Wang, Hui Wang, Xijie Ye, Zicheng Huang, Keli Yang   +10 more
wiley   +1 more source

Clostridium difficile Infection

Clinical and Translational Gastroenterology, 2015
Clostridium difficile infection (CDI) affects a broad population and has become so widespread the Centers for Disease Control and Prevention rated C. difficile as an urgent threat in 2013.1, 2 Recent basic-science research has focused on understanding the pathogenesis of the disease and alterations in the microbiome causing susceptibility.
openaire   +3 more sources

Successful treatment of Pseudescherichia vulneris‐associated acute haemorrhagic diarrhoea with a single faecal microbiota transplantation in a dog

Veterinary Record Case Reports, EarlyView.
Abstract An 8‐year‐4‐month‐old, female, neutered labrador retriever with acute haemorrhagic diarrhoea was unresponsive to symptomatic and antibiotic treatment, and developed gastrointestinal protein loss leading to significant hypoalbuminaemia.
Luis Miguel Garcia Roldan, Glynn Woods, Julien Dandrieux, Silke Salavati Schmitz   +3 more
wiley   +1 more source