Results 91 to 100 of about 55,569 (166)

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

Effects of Clostridium perfringens iota toxin in the small intestine of mice [PDF]

open access: yes, 2017
Iota toxin is a binary toxin solely produced by Clostridium perfringens type E strains, and is structurally related to CDT from C. difficile and CST from C. spiroforme.
Bruzzone, Octavio Augusto   +8 more
core   +1 more source

Vonoprazan pharmacokinetics and effects on gastric pH following administration to fed and fasted horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Current treatment options for equine gastric ulcer syndrome (EGUS), such as omeprazole—a proton pump inhibitor (PPI)—have notable limitations, including the need for administration on an empty stomach. Potassium‐competitive acid blockers (P‐CABs), such as vonoprazan, are a newer class of acid suppressants that offer several ...
Camilo J. Morales   +4 more
wiley   +1 more source

Clostridium difficile infection in the United States: A national study assessing preventive practices used and perceptions of practice evidence [PDF]

open access: yes, 2015
We surveyed 571 US hospitals about practices used to prevent Clostridium difficile infection (CDI). Most hospitals reported regularly using key CDI prevention practices, and perceived their strength of evidence as high.
Dubberke, Erik R   +6 more
core   +2 more sources

A retrospective clinical study on the influencing factors of Clostridium difficile infection in elderly patients

open access: yesGuoji laonian yixue zazhi
[Objective] To investigate the risk factors of Clostridium difficile infection in elderly inpatients and provide the theoretical basis for the prevention and treatment of Clostridium difficile infection.
Yang Chen   +7 more
doaj   +1 more source

Clostridium difficile on YouTube: A need for greater focus on prevention

open access: yesJournal of Infection and Public Health, 2018
The purpose of this study was to describe the content of the most popular YouTube videos related to Clostridium difficile. Across all sources, the kinds of content most likely to be included in the videos was general information, overuse of antibiotics ...
Corey H. Basch   +3 more
doaj   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Draft Genome Sequences of Five Enterococcus Species Isolated from the Gut of Patients with Suspected Clostridium difficile Infection [PDF]

open access: yes, 2017
Indexación: Scopus.We present draft genome sequences of five Enterococcus species from patients suspected of Clostridium difficile infection. Genome completeness was confirmed by presence of bacterial orthologs (97%).
Baquedano, S.   +5 more
core   +1 more source

Clostridium difficile Outbreaks [PDF]

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2007
To the Editor: The seriousness of Clostridium difficile outbreaks in Montreal, Quebec, and other areas of Quebec has been well described in the recent literature (1,2). Currently, a hypervirulent strain of C difficile is making its presence felt, causing morbidity and mortality related to C difficile-associated disease (CDAD).
openaire   +3 more sources

Histiocytes: Multifaceted Regulators of Health and Disease

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

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