Results 121 to 130 of about 110,558 (326)

Have we hit the JAK‐pot? Success of selective JAK 1 inhibitor following failure of pan‐JAK inhibitor in refractory pediatric ulcerative colitis

JPGN Reports, EarlyView.
Abstract The treatment options available for pediatric ulcerative colitis (UC) are challenging due to few with Federal Drug Administration approval. Newer medications approved for adults include additional biologics with differing mechanisms of action and small molecule drugs, such as Janus kinase (JAK) inhibitors.
Jessica A. Black, Brad Pasternak
wiley   +1 more source

A retrospective clinical study on the influencing factors of Clostridium difficile infection in elderly patients

Guoji laonian yixue zazhi
[Objective] To investigate the risk factors of Clostridium difficile infection in elderly inpatients and provide the theoretical basis for the prevention and treatment of Clostridium difficile infection.
Yang Chen, Yingjun Gong, Cui Li, Huan Li, Jia Chen, Hui Su, Xiaoming Wang, Xiaoxuan Ning   +7 more
doaj   +1 more source

Liver Disease Predicts 30‐Day Postoperative Complications in Head and Neck Microvascular Surgery

The Laryngoscope, EarlyView.
While liver disease is known to affect surgical outcomes, its impact on head and neck microvascular free tissue transfer surgeries remains unexamined. This study uses the NSQIP national database to analyze the relationship between liver disease severity, determined by APRI and MELD‐Na scores, and postoperative complications.
Anish R. Kosanam, James R. Xu, Khashayar Arianpour, Danielle Bottalico, Eric D. Lamarre   +4 more
wiley   +1 more source

Faecal microbiota transplantation : a regulatory hurdle? [PDF]

, 2017
During faecal microbiota transplantation, stool from a healthy donor is transplanted to treat a variety of dysbiosis-associated gut diseases. Competent authorities are faced with the challenge to provide adequate regulation.
De Spiegeleer, Bart, Janssens, Yorick, Verbeke, Frederick, Wynendaele, Evelien   +3 more
core   +2 more sources

The Gut‐Brain Axis in Parkinson disease: Emerging Concepts and Therapeutic Implications

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The gut‐brain axis, i.e. the bidirectional communication system between the gut and the brain, has become of central importance in Parkinson disease (PD) research over the past 20 years. Aims We aimed to describe the milestones of the gut‐brain axis research in PD and the development of theories proposing the involvement of the ...
Elisa Menozzi, Anthony H.V. Schapira, Per Borghammer   +2 more
wiley   +1 more source

Characterization of the Adherence of Clostridium difficile Spores: The Integrity of the Outermost Layer Affects Adherence Properties of Spores of the Epidemic Strain R20291 to Components of the Intestinal Mucosa [PDF]

, 2016
Indexación: Web of Science.Clostridium difficile is the causative agent of the most frequently reported nosocomial diarrhea worldwide. The high incidence of recurrent infection is the main clinical challenge of C. difficile infections (CBI). Formation of
Banawas, Saeed, Calderón, Iván, Castro-Córdova, Pablo, Fuentes, Juan A., Gil, Fernando, Miranda-Cárdenas, Camila, Mora-Uribe, Paola, Paredes-Sabja, Daniel, Rodas, Paula I., Sarker, Mahfuzur R.   +9 more
core   +2 more sources

Nickel (II) Ions Interaction with Polynucleotides and DNA of Different GC Composition [PDF]

arXiv, 2009
The goal of the work was to study the role of GC alternative dimmers in the binding of DNA with Ni (II) ions. The method of ultraviolet difference spectroscopy has been applied to investigate Ni (II) ions interactions with DNA extracted from Clostridium perfringens, Mice liver (C3HA line), Calf thymus, Salmon sperm, Herring sperm, E.coli, Micrococcus ...
arxiv  

Effects of Natural Polysaccharides on the Gut Microbiota Related to Human Metabolic Health

Molecular Nutrition &Food Research, EarlyView.
The graphical abstract illustrates the role of polysaccharides extracted from various natural raw materials (such as mushrooms, marine organisms, fruits, and vegetables) in modulating the gut microbiota. The process begins with the extraction and purification of polysaccharides, followed by assessing their structure‐activity relationship. Upon entering
Yigang Huang, Hongfei Guo, Yuchen Liu, Wengang Jin, Chella Perumal Palanisamy, Jinjin Pei, Fatih Oz, A. M. Abd El‐Aty   +7 more
wiley   +1 more source

Prevalencia y factores relacionados con la infección por Clostridium difficile en un centro hospitalario de alta complejidad en Cali (Colombia)

Infectio
Resumen Objetivos: Estimar la prevalencia y los factores relacionados con la infección por Clostridium difficile en un hospital de alta complejidad en Cali (Colombia). Métodos: Se realizó un estudio de casos y controles en pacientes que consultaron por
José Millán Oñate-Gutiérrez, María Virginia Villegas, Adriana Correa   +2 more
doaj   +1 more source

Fecal microbiota transplantation in recurrent Clostridium difficile infection: the first prospective study of 30 patients in Romania

Romanian Journal of Laboratory Medicine, 2018
Introduction: The infection with Clostridium difficile has increased in incidence worldwide and it raises many problems with regard to therapy, resistance to treatment and especially recurrence.
Mihaela Laszlo, Pascu Oliviu, Leucuta Daniel-Corneliu, Andreica Vasile   +3 more
doaj   +1 more source