Results 41 to 50 of about 47,365 (201)
An atypical case of infection by Clostridium difficile
Clostridium difficile is a Gram-positive human pathogenic bacterium and nosocomial pathogen; it is the causative agent diarrhoea, colitis and pseudo-membranous colitis associated with antibiotic therapy.
Maria Cristina Neri +5 more
doaj +1 more source
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen +4 more
wiley +1 more source
Role of Microbiota and Innate Immunity in Recurrent Clostridium difficile Infection
Recurrent Clostridium difficile infection represents a burdensome clinical issue whose epidemiology is increasing worldwide. The pathogenesis is not yet completely known.
Stefano Bibbò +5 more
doaj +1 more source
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga +20 more
wiley +1 more source
Background Recurrent Clostridium difficile infection is a growing problem among children due to both the increasing survival of medically fragile children with complicated chronic medical conditions resulting in prolonged antibiotic exposure and ...
D. E. Dow, P. C. Seed
doaj +1 more source
Clostridioides difficile is an anaerobic pathogen that causes significant morbidity and mortality. Understanding the mechanisms of colonization resistance against C. difficile is important for elucidating the mechanisms by which C.
Amber D. Reed, Casey M. Theriot
doaj +1 more source
Controlling Clostridium difficile [PDF]
Clostridium difficile infection causes colitis and is closely associated with the use of antimicrobials, probably due to disruption of the normal bowel flora. Avoiding inappropriate antimicrobial use is the most important way to prevent this potentially life-threatening infection. Emergent hypervirulent variants of C.
McFarlane, Mark, Hajkowicz, Krispin
openaire +3 more sources
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber +7 more
wiley +1 more source
Infection Clostridium difficile as increasing epidemiological issue
Introduction: Clostridium difficile as an infectious agent of pseudomembranous enterocolitis, becomes more and more frequent problem among health facilities.
Maciej Rutkowski +3 more
doaj +3 more sources
Background By age three, 5%–75% of children have a documented antibiotic allergy (AL). Despite this prevalence, recognition remains low because of limited clinician knowledge and time. Our study evaluates a novel approach to identifying AL using electronic medical record (EMR) prescription patterns.
Georgia Koutsaplis +5 more
wiley +1 more source

