Results 51 to 60 of about 64,708 (238)

Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Understanding the genetic links between acute pancreatitis (AP) and its infectious comorbidities is crucial for prognosis and therapy, yet remains underexplored. Methods We conducted a comprehensive post‐GWAS analysis using large‐scale summary statistics for AP and 16 infectious diseases. To pinpoint pleiotropic genes, we integrated
Bo Zou, Hao Jiang, Jingsheng Ruan, Daifeng Yang, Xing Chen, Shanshan Cai, Xinglin Yi   +6 more
wiley   +1 more source

Examination of Clostridium difficile Contamination in beef meat distributed in Isfahan using culture and Multiplex-PCR method

Biological Journal of Microorganism, 2014
Introduction: With regard to increasing of community associated Clostridium difficile infection in recent years, the probable transmission of Clostridium difficile from food to human was supposed.
zahra Esfandiari, Mohammad Jalali, Hamid Ezzatpanah, Scott Weese, Mohammad Chamani   +4 more
doaj  

Isolated gastrointestinal Langerhans cell histiocytosis in a 16‐month‐old child: A case report

JPGN Reports, EarlyView.
Abstract Langerhans cell histiocytosis (LCH) is a rare disorder characterized by clonal proliferation of Langerhans cells, most often involving the skin or bone. Isolated gastrointestinal (GI) involvement is extremely uncommon in young children. We report a 16‐month‐old girl with a 1‐month history of chronic vomiting, bloody diarrhea, and failure to ...
Al‐Qasim AL‐Bahlani, Laraib Touseeq, Mohammed Al‐Masqari, Emad Saad   +3 more
wiley   +1 more source

Toxic megacolon: A rare presentation and novel treatment

JPGN Reports, EarlyView.
Abstract A 14‐year‐old male presented with toxic megacolon (TM). Stool culture and rectal biopsies ruled out Clostridium difficile infection and Hirschsprung disease, respectively. Anorectal manometry ruled out anal achalasia as rectoanal inhibitory reflex elicited a normal resting pressure.
Adrienne P. Davis, Jennifer M. Schuh, Janice Bitong, Amy J. Wagner   +3 more
wiley   +1 more source

A Rare Case of Pseudomembranous Colitis Presenting with Pleural Effusion and Ascites with Literature Review

Case Reports in Gastrointestinal Medicine, 2021
Clostridium difficile infection usually results from long-term and irregular antibiotic intake. The high-risk individuals for this infection include the patients undergoing chemotherapy due to malignancy, immunocompromised patients, and hospitalized ...
Hossain Salehi, Amir Mohammad Salehi
doaj   +1 more source

Das difficile Clostridium / The difficile Clostridium

LaboratoriumsMedizin, 2008
Zusammenfassung Clostridium difficile ist nach 3–5 Tagen Krankenhausaufenthalt der bedeutendste Erreger für infektiöse Durchfallerkrankungen und die am häufigsten diagnostizierte Ursache von Durchfällen. Die Epidemiologie der Clostridium difficile assoziierten Durchfälle (CDAD) beginnt sich zu ändern.
Christoph von Eichel-Streiber, Veit Braun   +1 more
openaire   +1 more source

Gastrointestinal manifestations following chimeric antigen receptor T‐cell (CAR‐T) 19 therapy in pediatric patients with CD19+ acute lymphoblastic leukemia

JPGN Reports, EarlyView.
Abstract Pediatric patients with CD19+ acute lymphoblastic leukemia (ALL) undergoing chimeric antigen receptor T‐cell (CAR‐T) therapy frequently experience gastrointestinal (GI) complications. A retrospective study analyzed 13 patients (median age: 8 years) treated between January 2020 and January 2024.
Judith Raya Muñoz, Melissa Panesso Romero, Saray Mesonero Cavia, Marta Freixas Bermejo, Vanessa Cabello Ruiz, Marina Álvarez Beltran, Maria Cristina Díaz de Heredia Rubio, Susana Elena Redecillas Ferreiro, Oscar Segarra Canton   +8 more
wiley   +1 more source

Antibiotic Associated Diarrhea in Hospitalized Adult Patients

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2018
Background: Antibiotic associated diarrhea (AAD) occurs from the first initiation until 2 months of the end of antibiotic treatment. The aims of this study were to know the incidence of AAD, Clostridium difficile infection and other gastrointestinal ...
Marcellus Simadibrata, Lie Khie Chen, Diana Aulia, Ina Sutanto Timan   +3 more
doaj   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Recurrent Pseudomembranous Colitis in an Ovarian Cancer Patient Undergoing Carboplatin Chemotherapy

Case Reports in Obstetrics and Gynecology, 2016
Background. Diarrhea is a common problem in ovarian cancer patients undergoing chemotherapy and Clostridium difficile infection has been identified as a cause.
Valerie A. Allen, Kelly J. Manahan, John P. Geisler   +2 more
doaj   +1 more source