Results 51 to 60 of about 34,415 (160)

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen   +4 more
wiley   +1 more source

Clostridium difficile infection in the United States: A national study assessing preventive practices used and perceptions of practice evidence [PDF]

open access: yes, 2015
We surveyed 571 US hospitals about practices used to prevent Clostridium difficile infection (CDI). Most hospitals reported regularly using key CDI prevention practices, and perceived their strength of evidence as high.
Dubberke, Erik R   +6 more
core   +2 more sources

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse   +3 more
wiley   +1 more source

Emerging trends in 'smart probiotics' : functional consideration for the development of novel health and industrial applications [PDF]

open access: yes, 2017
The link between gut microbiota and human health is well-recognized and described. This ultimate impact on the host has contributed to explain the mutual dependence between humans and their gut bacteria.
El Hage, Racha   +2 more
core   +3 more sources

The management of Clostridium difficile infection [PDF]

open access: yesBritish Medical Bulletin, 2009
Clostridium difficile is the commonest cause of nosocomial diarrhoea. The epidemiology and clinical phenotype of the disease has dramatically changed with the global emergence of a virulent strain of C. difficile.This review was compiled using data from individual studies and review articles identified from PubMed.
O Martin, Williams, Robert C, Spencer
openaire   +2 more sources

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga   +20 more
wiley   +1 more source

Clostridium difficile Infection

open access: yesClinical and Translational Gastroenterology, 2015
Clostridium difficile infection (CDI) affects a broad population and has become so widespread the Centers for Disease Control and Prevention rated C. difficile as an urgent threat in 2013.1, 2 Recent basic-science research has focused on understanding the pathogenesis of the disease and alterations in the microbiome causing susceptibility.
openaire   +2 more sources

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber   +7 more
wiley   +1 more source

Effects of Clostridium difficile on the human immune response [PDF]

open access: yes, 2013
Clostridium difficile is a bacterium that is rapidly becoming a large issue in the medical community due to its tendency to infect hospital patients and its resistance to antibiotics.
McGovern, Mike
core   +1 more source

Clostridium difficile Infection

open access: yesMicrobiology Spectrum, 2016
ABSTRACT Clostridium difficile is an anaerobic, Gram-positive, spore-forming, toxin-secreting bacillus that has long been recognized to be the most common etiologic pathogen of antibiotic-associated diarrhea. C.
Jae Hyun, Shin   +2 more
openaire   +3 more sources

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