Results 71 to 80 of about 1,784,951 (230)

Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs

Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley   +1 more source

Nutritional and environmental determinants of maturation and disruption of the early life gut microbiome: A narrative review

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract The first 1000 days of life represent a critical window for gut microbiome assembly, with lifelong implications for child growth, immune development, and disease risk. This review synthesizes evidence on maternal, perinatal, and especially nutritional factors that influence early‐life intestinal colonization and highlights the consequences of ...
Carly Burow, Romy Shenderey, Fariha Chowdhury, Nyah Shah, Nikhil Pai   +4 more
wiley   +1 more source

Clostridium difficile Enterocolitis and Reactive Arthritis: A Case Report and Review of the Literature

Case Reports in Pediatrics, 2016
Reactive arthritis is a rare complication of Clostridium difficile enterocolitis, especially in children. We review the 6 pediatric cases published in the English and non-English literature and discuss their clinical presentation, outcome, treatment, and
Michela Cappella, Fabrizio Pugliese, Andrea Zucchini, Federico Marchetti   +3 more
doaj   +1 more source

Diarrhoea caused by Clostridium difficile in patients with postoperative subhepatic abscess [PDF]

Vojnosanitetski Pregled, 2008
Background. Toxigenic strains of Clostridium difficile in the majority of cases cause disease of the intestinal tract of hospitalized patients. For a long time, Clostridium difficile was considered to produce both types of toxins (A+/B+ strain), however,
Stojanović Predrag, Kocić Branislava
doaj   +1 more source

Gut microbiome in pediatric acute pancreatitis and Crohn's disease versus irritable bowel syndrome and healthy controls

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric acute pancreatitis (AP), Crohn's disease (CD), and irritable bowel syndrome (IBS) are associated with gut dysbiosis, but differences and similarities between conditions are unknown. We hypothesized that gut microbial ecology would differ across these disorders. Methods Stool was collected from 120 subjects (AP [n = 30], CD
Neha R. Santucci, Chinenye R. Dike, Jenny Hellmann, Nicholas J. Ollberding, Qing Duan, Philip Minar, Lee A. Denson, David B. Haslam, Daniel Castillo, Maisam Abu‐El‐Haija   +9 more
wiley   +1 more source

Pharmacokinetics of surotomycin from phase 1 single and multiple ascending dose studies in healthy volunteers

BMC Pharmacology and Toxicology, 2017
Background Surotomycin, a novel, orally administered, cyclic, lipopeptide antibacterial in development for the treatment of Clostridium difficile-associated diarrhea, has demonstrated minimal intestinal absorption in animal models.
Gurudatt Chandorkar, Qiao Zhan, Julie Donovan, Shruta Rege, Hernando Patino   +4 more
doaj   +1 more source

Microbiota Transplantation Effectively Treats Immune Checkpoint Inhibitor‐Associated Colitis: A Multi‐Center, Retrospective Case Series

Microbiota Medicine Research, EarlyView.
ABSTRACT Background Immune‐mediated colitis is an adverse effect of therapy with immune checkpoint inhibitors (ICIs). This study aims to evaluate the efficacy and safety of washed microbiota transplantation (WMT) in patients with ICI‐associated colitis.
Mengyu Huang, Yaping Liu, Hong Lu, Weihong Wang, Huiying Gao, Junlan Qiu, Yan Jin, Qian Ren   +7 more
wiley   +1 more source

Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors. [PDF]

, 2014
BACKGROUND: Bacterial sortases are transpeptidases that covalently anchor surface proteins to the peptidoglycan of the Gram-positive cell wall. Sortase protein anchoring is mediated by a conserved cell wall sorting signal on the anchored protein ...
Valiente, Esmeralda, Donahue, Elizabeth H, Major, Meriel R, Perrior, Trevor R, Firth-Clark, Stuart, Dawson, Lisa F, Littler, Eddy, Wren, Brendan W   +7 more
core   +1 more source

Guidelines for Clostridium difficile infection in adults [PDF]

, 2020
Clostridium difficile infection (CDI) has become a serious medical and epidemiological problem, especially in well developed countries. There has been evident increase in incidence and severity of CDI. Prevention, proper diagnosis and effective treatment
Michał Kukla, Grażyna Rydzewska, Kukla, Michał, Agnieszka Dobrowolska, Jarosław Reguła, Mach, Tomasz, Tomasz Mach, Dobrowolska, Agnieszka, Rydzewska, Grażyna, Adrych, Krystian, Krystian Adrych, Reguła, Jarosław   +11 more
core   +1 more source

Clostridium transplantifaecale sp. nov., a new bacterium isolated from patient with recurrent Clostridium difficile infection

New Microbes and New Infections, 2019
Clostridium transplantifaecale strain Marseille-P8228T (= CSURP8228) is a new species isolated from a patient with recurrent Clostridium difficile infection.
E.K. Yimagou, M.L. Tall, J.P. Baudoin, D. Raoult, J.Y. Bou Khalil   +4 more
doaj   +1 more source