Results 71 to 80 of about 1,868,246 (184)

Clostridium difficile Infection

Clinical and Translational Gastroenterology, 2015
Clostridium difficile infection (CDI) affects a broad population and has become so widespread the Centers for Disease Control and Prevention rated C. difficile as an urgent threat in 2013.1, 2 Recent basic-science research has focused on understanding the pathogenesis of the disease and alterations in the microbiome causing susceptibility.
openaire   +2 more sources

Development and Application of a Rapid 23S rRNA‐Targeted Reverse Transcription Quantitative PCR System for the Detection and Quantification of Enterobacterales

Microbiology and Immunology, EarlyView.
ABSTRACT Bacteria belonging to the family Enterobacteriaceae occur as commensals or pathogens in humans. The increasing prevalence of multidrug‐resistant bacteria has raised global concern. Following the reclassification of Enterobacteriaceae species into the order Enterobacterales in 2016.
Satomi Atobe, Mai Hane, Akira Takahashi, Yukiko Kado, Rie Date, Shuta Yamamoto, Takashi Asahara   +6 more
wiley   +1 more source

Clostridium difficile Enterocolitis and Reactive Arthritis: A Case Report and Review of the Literature

Case Reports in Pediatrics, 2016
Reactive arthritis is a rare complication of Clostridium difficile enterocolitis, especially in children. We review the 6 pediatric cases published in the English and non-English literature and discuss their clinical presentation, outcome, treatment, and
Michela Cappella, Fabrizio Pugliese, Andrea Zucchini, Federico Marchetti   +3 more
doaj   +1 more source

Pharmacokinetics of surotomycin from phase 1 single and multiple ascending dose studies in healthy volunteers

BMC Pharmacology and Toxicology, 2017
Background Surotomycin, a novel, orally administered, cyclic, lipopeptide antibacterial in development for the treatment of Clostridium difficile-associated diarrhea, has demonstrated minimal intestinal absorption in animal models.
Gurudatt Chandorkar, Qiao Zhan, Julie Donovan, Shruta Rege, Hernando Patino   +4 more
doaj   +1 more source

Diarrhoea caused by Clostridium difficile in patients with postoperative subhepatic abscess [PDF]

Vojnosanitetski Pregled, 2008
Background. Toxigenic strains of Clostridium difficile in the majority of cases cause disease of the intestinal tract of hospitalized patients. For a long time, Clostridium difficile was considered to produce both types of toxins (A+/B+ strain), however,
Stojanović Predrag, Kocić Branislava
doaj   +1 more source

Patient Safety and Organisational Accountability: Reassessing Criminal Liability Frameworks in Healthcare

The Modern Law Review, EarlyView.
Serious harm in healthcare often results from systemic failures, yet criminal accountability remains largely addressed through homicide law, gross negligence manslaughter and health‐and‐safety offences, frameworks that emphasise individual culpability and are ill‐suited to addressing organisational failings.
Sarah Bennett, Amel Alghrani
wiley   +1 more source

Collaborative Innovation and R&D Disclosures: Evidence From Co‐Patents Innovation collaborative et communication d'informations sur la R et D : données relatives à la copropriété de brevets

Contemporary Accounting Research, EarlyView.
ABSTRACT As firms increasingly rely on collaborative innovation to develop new technologies, they face a growing tension between signaling their technological capabilities and protecting sensitive information. This tension is especially important in co‐patenting settings, where firms jointly develop innovations and operate in a more interconnected ...
Caroline Lee, Zhongnan Xiang
wiley   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Equine coronavirus: Investigating seroconversion and faecal shedding patterns in naturally occurring field infections

Equine Veterinary Education, EarlyView.
Summary Background Equine coronavirus (ECoV) is an increasingly recognised cause of pyrexia and enteric disease in the horse. Objectives To (1) evaluate if horses seroconvert after clinical ECoV infection and (2) investigate the pattern of faecal excretion of ECoV to determine the optimal testing moment with the overall aim of helping veterinarians in ...
H. C. Smith, M. J. P. Theelen, R. M. A. C. Houben, R. van den Boom, L. van den Wollenberg, V. van Leeuwen, C. van Maanen   +6 more
wiley   +1 more source

The effect of the infection Clostridium difficile on the rehabilitation

Journal of Health Sciences, 2014
Introduction: Clostridium difficile is the cause of the post antibiotic colitis. This anaerobe, sporogenous, gram-positive bacteria is most often recognized as the cause of the nosocomial diarrhea.
Edina Tanovic, Haris Tanovic, Aldijana Kadic, Dževad Vrabac, Senad Selimović, Dragan Kostić   +5 more
doaj   +1 more source