Results 91 to 100 of about 1,868,246 (184)

Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors. [PDF]

, 2014
BACKGROUND: Bacterial sortases are transpeptidases that covalently anchor surface proteins to the peptidoglycan of the Gram-positive cell wall. Sortase protein anchoring is mediated by a conserved cell wall sorting signal on the anchored protein ...
Valiente, Esmeralda, Donahue, Elizabeth H, Major, Meriel R, Perrior, Trevor R, Firth-Clark, Stuart, Dawson, Lisa F, Littler, Eddy, Wren, Brendan W, Trevor R Perrior, Elizabeth H Donahue, Esmeralda Valiente, Meriel R Major, Lisa F Dawson, Eddy Littler, Stuart Firth-Clark, Brendan W Wren   +15 more
core   +2 more sources

The difficile in Clostridium difficile infection [PDF]

International Journal of Infectious Diseases, 2018
Garabet, Akoghlanian, Seetha, Lakshmi
openaire   +2 more sources

In Vitro Investigation of Auranofin as a Treatment for Clostridium difficile Infection

Drugs in R&D, 2020
Background Clostridium difficile infection is the leading cause of hospital-acquired gastrointestinal infection and incidence rates continue to rise. Clostridium difficile infection is becoming increasingly complex to treat owing to the rise in treatment
Christine Roder, Eugene Athan
doaj   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

A study of Clostridium difficile in biofilm mode of growth using the Sorbarod filter system [PDF]

In all ecosystems, bacteria are likely to grow in biofilms, and the organisms making up the natural flora of the colon are considered to be no exception to this. One of the most important hospital-acquired infections is antibiotic associated diarrhoea,
O'Connell, Nuala H.
core  

Emergence and global spread of epidemic healthcare-associated clostridium difficile [PDF]

, 2012
Epidemic C. difficile (027/BI/NAP1) has rapidly emerged in the past decade as the leading cause of antibiotic-associated diarrhea worldwide. However, the key events in evolutionary history leading to its emergence and the subsequent patterns of global ...
Hawkey, P.r, Brazier, Jon, Martin, Melissa J, Fairley, Derek, Brown, D., Kim, H.J., Kuijper, Ed, Kato, Haru, Coia, JE, Kathleen B Bamford, Tse Hsien Koh, Kim, HJ, He, M., Wren, B.W., Miyajima, Fabio, Riley, Tom, Brazier, J. S., Kato, H., Harris, Simon R, D'Arc, S., Butt, E., Nick M Brown, Gerding, D, Martin, M.J., Wren, BW, Paul Roberts, Douce, G, Pirmohamed, M, Munir Pirmohamed, Louise Ellison, Songer, Glen, Songer, G, Coia, John E., He, M, Brendan W Wren, Douce, Gill, Kuijper, E., Sharon J Peacock, Pickard, Derek J, Butt, Emma, Mark Wilcox, Lawley, Trevor D, Dale Gerding, Wren, Brendan W, Songer, G., Senoh, Mitsutoshi, Haru Kato, Mitsutoshi Senoh, D'Arc, S, Hee Jung Kim, Pirmohamed, M., Connor, Thomas Richard, Ellison, Louise, Brown, Nick M, Wilcox, Mark, Miyajima, F, Pickard, Derek J., Harris, S.R., Roberts, Paul, Koh, Tse Hsien, Melissa J Martin, Julian Parkhill, Hawkey, P., Louie, T., Bamford, KB, Coia, J., Dougan, Gordon, Coia, John E, Parkhill, Julian, Hawkey, P, Ed Kuijper, Bamford, Kathleen B., Thomas R Connor, Gill Douce, Glen Songer, Pickard, D.J., Simon R Harris, Tom Louie, Derek Fairley, Fairley, D, Miyajima, F., Wilcox, M, Parkhill, J, Michell, S., Tom Riley, Louie, Tom, Harris, Simon R., Louie, T, Lawley, T.D., Bamford, K.B., He, Miao, Gerding, Dale, Connor, T.R., Peacock, Sharon J., Kuijper, E, Butt, E, Peacock, SJ, Brown, Derek, Senoh, M., Gordon Dougan, Pirmohamed, Munir, Gerding, D., Ellison, L, Peter Hawkey, Koh, T.H., Harris, SR, Brazier, J., Wilcox, M., Trevor D Lawley, Coia, J.E., Emma Butt, Ellison, L., Peacock, Sharon J, Brown, NM, Michell, S, Derek Brown, Derek J Pickard, Brown, Nick M., 김희정, Martin, MJ, Peacock, S.J., Brown, N.M., Dougan, G., Brown, D, Riley, T., Kim, Hee Jung, Brazier, J, Kato, H, Connor, Thomas R, Fairley, D., Parkhill, J., Stephanie D'Arc, Wren, Brendan W., D'Arc, Stephanie, Douce, G., Lawley, TD, John E Coia, Fabio Miyajima, Michell, Stephen, Jon Brazier, Lawley, Trevor D., Martin, Melissa J., Miao He, Stephen Michell, Roberts, P., Koh, TH, Hawkey, Peter, Pickard, DJ, Bamford, Kathleen B, Douce, G.l, Roberts, P, Riley, T, Connor, TR, Senoh, M, Dougan, G   +154 more
core   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Clostridium difficile ribotypes in Austria: a multicenter, hospital-based survey [PDF]

, 2015
A prospective, noninterventional survey was conducted among Clostridium difficile positive patients identified in the time period of July until October 2012 in 18 hospitals distributed across all nine Austrian provinces.
Hartmann, Gabriele, Silberbauer, Karl, Markus Hell, Urban, Astrid, Steliana Huhulescu, Daniela Schmid, Indra, Alexander, Pap, Ildiko-Julia, Masoud, Helga, Equiluz-Bruck, Susanne, Gilhofer, Monika, Huhulescu, Steliana, Bischof, Elisabeth, Lenger, Andrea, Janata, Oskar, Aspöck, Christophe, Stoiser, Brigitte, Pomper, Ulrike, Wechsler-Fördös, Agnes, Geppert, Friederike, König, Uwe, Feierl, Gebhard, Karl Stickler, Simons, Erica, Hell, Markus, Szupancsitz, Maria, Erica Simons, Schmid, Daniela, Höfler-Speckner, Simone, Allerberger, Franz, Leeb, Monika, Reiter, Lukas, Zeitlberger, Eva-Maria, Assadian, Ojan, Prammer, Wolfgang, Franz Allerberger, Stickler, Karl, Alexander Indra, null null, Tucek, Gerhard, Orth, Dorothea, Stradal, Heinz, Tomantschger, Herwig   +42 more
core   +1 more source

Pseudomembranous colitis

Journal of Pathology of Nepal, 2019
Pseudomembranous colitis is an inflammatory condition of the colon that is most often a manifestation of Clostridium difficile infection. If laboratory testing and endoscopic finding for Clostridium difficile infection is negative, then other less common
Devish Pyakurel
doaj   +1 more source

Targeting B‐Cell‐Activating Factor and Its Receptor in Immune Thrombocytopenia and Warm Autoimmune Hemolytic Anemia

American Journal of Hematology, Volume 101, Issue 11, Page 2836-2852, November 2026.
ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas, Nichola Cooper, Vickie McDonald, Karina Yazdanbakhsh, Wilma Barcellini   +4 more
wiley   +1 more source