Results 101 to 110 of about 1,868,246 (184)

Development of a novel method for detection of C. difficile using HS-SPME-GC-MS [PDF]

, 2014
AIMS:A novel method has been developed that allows successful differentiation between Clostridium difficile culture-positive and culture-negative stool samples based on volatile organic compound (VOC) evolution and detection by headspace solid-phase ...
Dean, John, Stanforth, Stephen, Tait, Emma, Hill, Kerry, Perry, John   +4 more
core   +1 more source

Antibiotic therapy and clostridium difficile infection – primum non nocere – first do no harm [PDF]

, 2015
Treatment options for Clostridium difficile infection (CDI) remain limited despite this usually nosocomial infection posing an urgent threat to public health. A major paradox of the management of CDI is the use of antimicrobial agents to treat infection,
Crowther GS, Wilcox MH, Wilcox, MH, Crowther, G   +3 more
core   +1 more source

Application of the ATLAS score for evaluating the severity of Clostridium difficile infection in teaching hospitals in Mexico

Brazilian Journal of Infectious Diseases, 2015
Background: For clinicians, a practical bedside tool for severity assessment and prognosis of patients with Clostridium difficile infection is a highly desirable unmet medical need. Setting: Two general teaching hospitals in northeast Mexico. Population:
Raúl Hernández-García, Elvira Garza-González, Mark Miller, Giovanna Arteaga-Muller, Alejandra María Galván-de los Santos, Adrián Camacho-Ortiz   +5 more
doaj   +1 more source

Lachnospiraceae in the Food–Gut Axis: A Critical Review of Dietary Modulation, Immune Regulation, and Translational Barriers

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT The interplay between diet, gut microbiota, and host immunity is central to food science. The Lachnospiraceae family ferments dietary fibers to produce short‐chain fatty acids (SCFAs), notably butyrate and propionate, with immunomodulatory potential. This critical review distinguishes established findings from hypotheses.
Ruijun Wang, Zhiqi Li, Lina Zhang, Yuanming Pan, Zhanbiao He   +4 more
wiley   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, Volume 13, Issue 55, 5 October 2026.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Clostridium difficile Infection

Microbiology Spectrum, 2016
ABSTRACT Clostridium difficile is an anaerobic, Gram-positive, spore-forming, toxin-secreting bacillus that has long been recognized to be the most common etiologic pathogen of antibiotic-associated diarrhea. C.
Jae Hyun, Shin, Esteban, Chaves-Olarte, Cirle A, Warren   +2 more
openaire   +3 more sources

Combination of oral vancomycin and intra-colonic vancomycin: Successful treatment of complicated pseudomembranous colitis in a child patient

SAGE Open Medical Case Reports, 2019
The Clostridium difficile infection–related disease varies from mild diarrhoea to pseudomembranouscolitis. Although C. difficile infection is commonly considered to be a hospital-acquired infection, a significant number of cases are community acquired ...
Hüseyin Sancar Bozkurt, Banu Kara
doaj   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, Volume 13, Issue 55, 5 October 2026.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source

Characteristics of patients with Clostridium difficile infection in Taiwan

, 2014
The medical records of 84 patients with stool cultures positive for Clostridium difficile during the period August 2007 to June 2009 were retrospectively reviewed. A case of confirmed (toxigenic) C.
薛博仁 ;李岱芬, Lin, Y. -C.;Huang, Y. -T.;Lee, T. -F.;Lee, N. -Y.;Liao, C. -H.;Lin, S. -Y.;Ko, W. -C.;Hsueh, P. -R.   +1 more
core   +1 more source

How do hospital professionals involved in a randomised controlled trial perceive the value of genotyping vs. PCR-ribotyping for control of hospital acquired C. difficile infections? [PDF]

, 2014
Background: Despite scientific advances in typing of C. difficile strains very little is known about how hospital staff use typing results during periods of increased incidence (PIIs). This qualitative study, undertaken alongside a randomised controlled
Peter M Hawkey, Hawkey, Peter M., Szczepura, Ala, Parsons, Helen, Katherine Hardy, Susan Manzoor, Gossain, Savita, Savita Gossain, Hardy, K. (Katherine), Stallard, Nigel, Nigel Stallard, Manzoor, Susan, Ala Szczepura, Hardy, Katherine, Helen Parsons, Hawkey, P. M. (Peter M.), Szczepura, Ala; id_orcid   +16 more
core   +2 more sources